Home › Myelodysplastic Syndromes › NCT07469592

eHealth Mindfulness-based Music Therapy Intervention for Patients Undergoing Stem Cell Transplantation

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* ≥ 18 years of age
* have a primary diagnosis of a hematologic malignancy (e.g., myelodysplastic syndrome \[MDS\], acute myeloid leukemia \[AML\], acute lymphoblastic leukemia \[ALL\], or non Hodgkin's Lymphoma \[NHL\])
* have a treatment plan for a hematopoietic stem cell transplant
* Speak English or Spanish

Exclusion Criteria:

* history of severe psychiatric illness (e.g., psychosis, active suicidality, inpatient treatment in the past 12 months)
* severe cognitive impairment (per the short portable mental status questionnaire)
* hearing impairment
* active alcohol or substance dependence within the past six months
* participated in the prior pilot MBMT R61 phase
* participated in music therapy or mindfulness programs in the past six months

About the study

The goal of this study is to test an electronic health (eHealth) mindfulness-based music therapy intervention to improve health-related quality of life and reduce symptom burden and disease activity in patients undergoing stem cell transplantation.

What is being tested

• eHealth Mindfulness-based Music Therapy (eMBMT) (behavioral)
• eHealth Mindfulness Meditation (eMM) (behavioral)

Sponsor: University of Miami · Participants: 165 · Started: Jul 22, 2026

Contact the study team

• Frank J Penedo, PhD · Phone: (305) 284-4290
• Sara E Fleszar-Pavlovic, PhD · Phone: (305) 243-4009

Official record on ClinicalTrials.gov — NCT07469592

Locations in the U.S.

Conditions

• Myelodysplastic Syndromes
• Acute Myeloid Leukemia
• Acute Lymphoblastic Leukemia
• Non-Hodgkin Lymphoma

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.