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A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease

Clinical Implications of Pulmonary Vascular Disease in Valvular Heart Disease

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* ≥18 years old; AND
* Scheduled for valve procedures

Exclusion Criteria:

* Congenital heart disease (except for bicuspid aortic valve), OR
* Carcinoid heart disease, OR
* Valvular mass, OR
* Endocarditis, OR
* Any other condition that, in the opinion of the investigator, would impair their ability to complete the study

About the study

The purpose of this study is to characterize pulmonary hemodynamic profiles, with a focus on PVR subtypes, in patients with left-sided valvular heart disease undergoing aortic or mitral valve intervention, and to identify patterns predicting reversibility of TR and RV dysfunction.

What is being tested

• Echocardiogram (diagnostic test)

Sponsor: Mayo Clinic · Participants: 600 · Started: Apr 28, 2026

Contact the study team

• Annabelle Fuenffinger · Phone: 507-422-3801

Official record on ClinicalTrials.gov — NCT07483203

Locations in the U.S.

Conditions

• Heart Valve Diseases

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.