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Heart Valve Diseases clinical trials recruiting in the U.S.
29 studies for Heart Valve Diseases are recruiting participants at sites across the United States.
Heart valve disease happens when one or more of your heart valves do not open or close correctly. This can affect your blood flow and strain your heart.
Cities with the most studies
- New York City, NY12 studies
- Cleveland, OH11 studies
- Cincinnati, OH6 studies
- Phoenix, AZ5 studies
- Boston, MA5 studies
- Philadelphia, PA5 studies
- Atlanta, GA5 studies
- Chicago, IL5 studies
- Minneapolis, MN5 studies
- Houston, TX4 studies
- Los Angeles, CA4 studies
- Pittsburgh, PA4 studies
- New Orleans, LA4 studies
- Ann Arbor, MI4 studies
- Washington, DC4 studies
- Nashville, TN3 studies
- Columbus, OH3 studies
- Harrisburg, PA3 studies
- Portland, OR3 studies
- Baltimore, MD3 studies
- St. Louis, MO3 studies
- The Bronx, NY3 studies
- Seattle, WA3 studies
- Thousand Oaks, CA3 studies
- Durham, NC3 studies
By state
- Arizona5 studies
- California8 studies
- Connecticut3 studies
- Florida3 studies
- Georgia6 studies
- Illinois7 studies
- Kansas3 studies
- Louisiana4 studies
- Maryland4 studies
- Massachusetts5 studies
- Michigan5 studies
- Minnesota8 studies
- Missouri4 studies
- New Jersey5 studies
- New York12 studies
- North Carolina4 studies
- Ohio14 studies
- Oregon3 studies
- Pennsylvania7 studies
- Tennessee3 studies
- Texas5 studies
- Virginia5 studies
- Washington3 studies
- Wisconsin3 studies
Recently updated studies
EFS of the DUO System for Tricuspid Regurgitation
Recruiting
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05913908CTSN Embolic Protection Trial
Recruiting
Ages 60 and older · All sexes · Updated Sep 28, 2026 · NCT06027788Capitalizing on AI to CapTure Undiagnosed Structural Heart Disease
Recruiting
Ages 40 and older · All sexes · Updated Sep 25, 2026 · NCT07843004Medtronic Cardiac Surgery PMCF Registry
RecruitingObservational study
All ages · All sexes · Updated Sep 25, 2026 · NCT04073420Transcatheter Tricuspid Valve Replacement With the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in Severe Tricuspid Regurgitation
Recruiting
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07321899Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06033274Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging
RecruitingObservational studyHealthy volunteers welcome
Ages 7 to 100 · All sexes · Updated Sep 8, 2026 · NCT03581318Paired-Ring Mitral Annuloplasty Ring Sizing Device
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06965725Home-Based Cardiac Rehabilitation Using a Novel Mobile Health Exercise Regimen Following Transcatheter Heart Valve Interventions
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06077201Abbott Structural Heart Device Registry
RecruitingObservational study
All ages · All sexes · Updated Sep 1, 2026 · NCT06590467VDyne Transcatheter Tricuspid Valve Replacement Study to Evaluate Safety and Clinical Efficacy in Patients With Symptomatic Severe Tricuspid Valve Regurgitation (TRIVITA Pivotal Trial)
Recruiting
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07516444Longitudinal Validation of CIRC Technologies
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07081711The TRICURE EFS Study
Recruiting
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06506942A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT07483203AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT06699056Development of CIRC Technologies
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT05654272DeBakey Cardiovascular Magnetic Resonance Study
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Apr 20, 2026 · NCT04281823DELINEATE-Prospective
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT07197736The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152Observational Study of Patients Undergoing Diagnostic Right Heart Catheterization
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT07224906PPG to Predict Ejection Fraction and Other Echographic Data in the General Population
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 120 · All sexes · Updated Mar 5, 2026 · NCT04843371Mosaic Mitral Valve: Long-Term Outcomes in Patients Under 65
RecruitingObservational study
Ages 18 to 65 · All sexes · Updated Feb 20, 2026 · NCT06917586Comparative Imaging Assessment of Valvular Heart Disease
RecruitingObservational study
Ages 18 to 90 · All sexes · Updated Jan 13, 2026 · NCT04126018Transpacific TAVR Registry
RecruitingObservational study
Ages 19 and older · All sexes · Updated Jan 2, 2026 · NCT03826264From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.