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Heart Valve Diseases clinical trials recruiting in the U.S.

29 studies for Heart Valve Diseases are recruiting participants at sites across the United States.

Heart valve disease happens when one or more of your heart valves do not open or close correctly. This can affect your blood flow and strain your heart.

Cities with the most studies

By state

Recently updated studies

EFS of the DUO System for Tricuspid Regurgitation

Recruiting
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05913908

CTSN Embolic Protection Trial

Recruiting
Ages 60 and older · All sexes · Updated Sep 28, 2026 · NCT06027788

Capitalizing on AI to CapTure Undiagnosed Structural Heart Disease

Recruiting
Ages 40 and older · All sexes · Updated Sep 25, 2026 · NCT07843004

Medtronic Cardiac Surgery PMCF Registry

RecruitingObservational study
All ages · All sexes · Updated Sep 25, 2026 · NCT04073420

Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06033274

Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging

RecruitingObservational studyHealthy volunteers welcome
Ages 7 to 100 · All sexes · Updated Sep 8, 2026 · NCT03581318

Paired-Ring Mitral Annuloplasty Ring Sizing Device

RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06965725

Abbott Structural Heart Device Registry

RecruitingObservational study
All ages · All sexes · Updated Sep 1, 2026 · NCT06590467

Longitudinal Validation of CIRC Technologies

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07081711

The TRICURE EFS Study

Recruiting
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06506942

A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease

RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT07483203

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT06699056

Development of CIRC Technologies

RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT05654272

DeBakey Cardiovascular Magnetic Resonance Study

RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Apr 20, 2026 · NCT04281823

DELINEATE-Prospective

RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT07197736

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Observational Study of Patients Undergoing Diagnostic Right Heart Catheterization

RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT07224906

PPG to Predict Ejection Fraction and Other Echographic Data in the General Population

RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 120 · All sexes · Updated Mar 5, 2026 · NCT04843371

Mosaic Mitral Valve: Long-Term Outcomes in Patients Under 65

RecruitingObservational study
Ages 18 to 65 · All sexes · Updated Feb 20, 2026 · NCT06917586

Comparative Imaging Assessment of Valvular Heart Disease

RecruitingObservational study
Ages 18 to 90 · All sexes · Updated Jan 13, 2026 · NCT04126018

Transpacific TAVR Registry

RecruitingObservational study
Ages 19 and older · All sexes · Updated Jan 2, 2026 · NCT03826264

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.