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The Relationship Between Blood Flow Readings During Surgery and How Well the Graft Stays Open and How Patients Recover Afterward in Coronary Artery Bypass Graft Surgery

Surgical Measurement for Accurate Revascularization Using Transit-time FLOW (SMARTFLOW):Patency

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

1. Age \>18 years
2. First-time, non-emergent isolated multivessel CABG through median sternotomy
3. Willing and able to provide written informed consent and comply with all study procedures, including QOL questionnaires

Exclusion Criteria:

1. Reoperation
2. Emergency procedures
3. Combined CABG + other cardiac or non-cardiac surgery
4. Isolated single vessel CABG
5. Minimally invasive CABG
6. Inability to undergo coronary computed tomographic angiography (CCTA)
7. Unable to provide written informed consent or comply with all the study procedures.

About the study

The purpose of this study is to learn more about a tool called Transit-Time Flow Measurement (TTFM). TTFM uses sound waves during surgery to check how well blood is flowing through blood vessels. This helps doctors see if the blood flow is good during coronary artery bypass grafting (CABG), which is a type of heart surgery

What is being tested

• Transit-Time Flow Measurement (TTFM) (device)

Sponsor: Weill Medical College of Cornell University · Participants: 1,242 · Started: Mar 30, 2026

Contact the study team

• SMARTFLOW Trial Listserv · Phone: (212) 746-5460

Official record on ClinicalTrials.gov — NCT07485738

Locations in the U.S.

Conditions

• Heart Diseases

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.