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HABIT-ILE + FST in Children With SMA: Preliminary Effectiveness

Feasibility and Preliminary Effectiveness of HABIT-ILE + Functional Strength Training in Children With Spinal Muscular Atrophy (SMA): a Prospective Single-group Intervention Trial.

Who can join

Ages 5 to 17 · All sexes

Inclusion Criteria:

* Have a confirmed SMA diagnosis
* Be 5-17 years old
* Complete all pre- and post-intervention assessments
* Understand and speak English
* Follow instructions without major cognitive or behavioral issues
* Have received a stable disease-modifying therapy (DMT) dose for ≥6 months
* Be classified as a sitter or walker (SMA type 2 or 3) with supported standing ability (score ≥1 on Item 18 of the HFMSE) without KAFOs, AFOs, or external standing devices

Exclusion Criteria:

* Orthopedic surgery within the past year
* New pharmaceutical treatment during the study
* Concurrent participation in another clinical trial

About the study

This single-arm pilot study will assess the preliminary effectiveness of an intensive motor skill intervention (HABIT-ILE) combined with functional strength training (FST) in children with SMA who are receiving disease-modifying therapies. Participants will attend a HABIT-ILE + FST summer camp for 6 hours per day over a 3-week period, totaling 90 hours of training.

What is being tested

• Combined Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) + functional strength training (FST) (other)

Sponsor: Teachers College, Columbia University · Participants: 20 · Started: Mar 15, 2026

Contact the study team

• Andrew M Gordon, PhD · Phone: +1(212) 678-3332

Official record on ClinicalTrials.gov — NCT07488338

Locations in the U.S.

Conditions

• Spinal Muscular Atrophy

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.