MucoLock™ for Treatment of Stomatitis

Inclusion Criteria:

* Age 18 years and older
* Individuals with oral dysesthesia (worst VAS sensitivity/burning score ≥ 7 over the last week)
* Ability to understand and the willingness to sign a written informed consent document

Exclusion Criteria:

* Inability to comply with study instructions
* Uncontrolled intercurrent illness or psychiatric illness/social situations that would limit compliance with study requirements\*
* Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the participant or the quality of the data.
* Advanced kidney disease
* Patients receiving antineoplastic therapy \[e.g., tyrosine kinase inhibitors (TKIs), radiation\] that could increase the risk of oral dysesthesia
* Known altered mental status, encephalopathy, or cognition impairment
* Ataxia
* Known alcohol use disorder
* Concomitant opioid therapy
* Diagnosis of oral cancer currently undergoing therapy
* Already using topical therapy for mouth pain (e.g., lidocaine, Magic mouthwash)\*
* Any opioid pain medication\*
* Treatment with another investigational drug or other intervention within 2 weeks. Patients will be recommended to stop previous medication for 2 weeks before starting the study treatment.

(asterisk) \*Modifiable criteria, with a timeframe of 2 weeks for a washout period.