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Health-Related Quality of Life and Metabolic Outcomes in PCOS

Health-Related Quality of Life and Metabolic Outcomes in PCOS: A Feasibility Study of Comprehensive PCOS Education and Lifestyle Modification Support Delivered Via Synchronous Virtual Groups

Who can join

Ages 18 to 49 · Women · Healthy volunteers welcome

Inclusion Criteria:

1. Non-pregnant females ages 18-49 years
2. Preexisting diagnoses of PCOS and obesity (body-mass index (BMI) equal or greater to 30 kg/m2) at enrollment

Exclusion Criteria:

1. Patients who are pregnant or planning to become pregnant during the study period
2. Patients currently or with recent participation (\< 12 months at the time of enrollment) in a PCOS-focused group
3. Patients with documented monogenic obesity
4. Patients with a diagnosis of any type of diabetes (with the exclusion of prediabetes)
5. Patients on systemic glucocorticoid therapy \> 7 days at the time of enrollment
6. Patients with any end-stage organ disease
7. Patients without access to internet
8. Patients requiring English language interpretation
9. Any condition which, based on the investigator's medical judgment, would preclude patient ability to complete the study

About the study

The primary outcome of interest is change in PCOS health-related quality of life, while the secondary outcome of interest is change in adiposity, cardiometabolic, and inflammation biomarkers.

What is being tested

• Intervention Group (other)

Sponsor: The Cleveland Clinic · Participants: 40 · Started: Jun 1, 2026

Contact the study team

• Andrea Parianos · Phone: 216-445-8354
• Amber Sike · Phone: 216-444-7551

Official record on ClinicalTrials.gov — NCT07571915

Locations in the U.S.

Conditions

• Polycystic Ovary Syndrome

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.