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Optimizing Pregnancy and Treatment Interventions for Moms 3.0

Recruiting

Randomized Trial: Optimizing Pregnancy and Treatment Interventions for Moms (OPTI-Mom) 3.0

Who can join

Ages 18 and older · Women

Full eligibility criteria
Inclusion Criteria:

* Adult (≥18 years)
* Opioid use disorder
* ≥7 weeks gestation
* Medication for opioid use disorder naive or newly initiated (≤6 weeks MOUD)
* Provide permission to access administrative claims and medical records of their care and those of their neonate
* Speak English

Exclusion Criteria:

* Plan to terminate pregnancy
* Had a psychotic and/or manic episode in the last 30 days
* Cannot provide contact information for themselves and 2 collateral contacts
* Do not possess a reliable phone
* Plan to move from the area ≤6 months of delivery
* \>32 weeks gestation

About the study

We want to learn if Patient Navigation helps pregnant Medicaid members with opioid use disorder, with or without stimulant use disorder, stay in care, use medications for opioid use disorder, reduce substance use, and connect with services, compared to usual care.

Enrolled participants will be randomly assigned (by chance, like flipping a coin) to one of two groups: Usual Care or Patient Navigation.

Participate will last up to 14 months and participants randomized to Patient Navigation may have about 14 sessions/calls with a Patient Navigator (30-45 minutes each) and complete 3 surveys (30-60 minutes each). All visits can be by phone or video.

What is being tested

Sponsor: University of Utah · Participants: 429 · Started: Jul 10, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07586917

Locations in the U.S.

UtahUniversity of Utah, Salt Lake City

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.