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Study of EVO756 in Adults With Migraine

RecruitingPhase 2

A Randomized, Double-Blind, Placebo Controlled Study Evaluating the Efficacy and Safety of EVO756 for the Prevention of Migraine in Adults

Who can join

Ages 18 to 64 · All sexes

Full eligibility criteria
Key Inclusion Criteria:

* Adults aged 18 to \<65 years
* Migraine with or without aura, per ICHD-3 criteria
* History of failure with prior preventive migraine treatments
* Not currently using migraine preventive therapy

Key Exclusion Criteria:

* Difficulty distinguishing migraine from other headache types or presence of other primary headache disorders
* Use of certain medications
* Any clinically significant medical, psychiatric, neurological, cardiovascular, or laboratory abnormalities

About the study

This study will evaluate the efficacy and safety of EVO756 against placebo in adults with migraine.

What is being tested

Sponsor: Evommune, Inc. · Participants: 330 · Started: Jul 29, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07616128

Locations in the U.S.

ArizonaTrialsphere Corp, Chandler
CaliforniaBuena Park Research Center, Buena Park
Neuro Pain Research Center, Fresno
CA Medical Clinic for Headache, Los Angeles
Diablo Clinical Research dba Flourish Research, Walnut Creek
ConnecticutNew England Institute for Neurology and Headache, Stamford
FloridaClinical Neuroscience Solutions, Inc., Jacksonville
Apple Medical Research Group, Inc, Miami
Blessed Healthcase & Research, Miami
Florida Research Center, Inc., Miami
Clinical Neuroscience Solutions, Inc., Orlando
Vantage Clinical Trials, Tampa
Premiere Research Institute at Palm Beach Neurology, West Palm Beach
GeorgiaAccel Research Site-Decatur-Alcanza, Decatur
MassachusettsMass Institute of Clinical Research, Westborough
MichiganMichigan Headache and Neurological Institute, Ann Arbor
Quest Research Institute-Alcanza, Farmington Hills
New JerseyBio Behavoural health, Toms River
New YorkClinosis - Dent Neurologic Instite, Amherst
North CarolinaAsheville Neurology Specialists, Pa, Asheville
Eximia Research NC, Raleigh
South CarolinaClinical Trials of South Carolina, Charleston
TexasFutureSearch Trials of Neurology, Austin
FutureSearch Trials of Dallas, Dallas
SFF Medical Research Group LLC, Houston
West VirginiaVaught Neurological Services, Crab Orchard

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.