Home › Migraine › NCT07616128
Study of EVO756 in Adults With Migraine
RecruitingPhase 2
A Randomized, Double-Blind, Placebo Controlled Study Evaluating the Efficacy and Safety of EVO756 for the Prevention of Migraine in Adults
Who can join
Ages 18 to 64 · All sexes
Full eligibility criteria
Key Inclusion Criteria:
* Adults aged 18 to \<65 years
* Migraine with or without aura, per ICHD-3 criteria
* History of failure with prior preventive migraine treatments
* Not currently using migraine preventive therapy
Key Exclusion Criteria:
* Difficulty distinguishing migraine from other headache types or presence of other primary headache disorders
* Use of certain medications
* Any clinically significant medical, psychiatric, neurological, cardiovascular, or laboratory abnormalities
About the study
This study will evaluate the efficacy and safety of EVO756 against placebo in adults with migraine.
What is being tested
- EVO756, Dose 1 (drug)
- EVO756, Dose 2 (drug)
- Placebo (drug)
Sponsor: Evommune, Inc. · Participants: 330 · Started: Jul 29, 2026
Contact the study team
Official record on ClinicalTrials.gov — NCT07616128
Locations in the U.S.
| Arizona | Trialsphere Corp, Chandler |
| California | Neuro Pain Research Center, Fresno
Salma Health La Jolla, La Jolla
CA Medical Clinic for Headache, Los Angeles
Diablo Clinical Research dba Flourish Research, Walnut Creek |
| Colorado | Denver Neurological Clinic, Denver |
| Connecticut | Hasbani Neurology, New Haven
New England Institute for Neurology and Headache, Stamford |
| Florida | Apple Medical Research Group, Inc, Miami
Blessed Healthcase & Research, Miami
Florida Research Center, Inc., Miami
Clinical Neuroscience Solutions, Inc., Orlando
Vantage Clinical Trials, Tampa
Premiere Research Institute at Palm Beach Neurology, West Palm Beach |
| Georgia | Clinical Integrative Research Center of Atlanta, Atlanta
Accel Research Site-Decatur-Alcanza, Decatur |
| Massachusetts | Neurology Center of New England P.C., Foxborough
Mass Institute of Clinical Research, Westborough |
| Michigan | Michigan Headache and Neurological Institute, Ann Arbor
Quest Research Institute-Alcanza, Farmington Hills |
| Nebraska | Papillion Research Center - Avacare Clinical Research, Papillion |
| New Jersey | Bio Behavoural health, Toms River |
| New York | Clinosis - Dent Neurologic Instite, Amherst |
| North Carolina | Asheville Neurology Specialists, Pa, Asheville
Eximia Research NC, Raleigh |
| Ohio | NeuroScience Research Center, Canton
Dayton Center for Neurological Disorders, Centerville |
| South Carolina | Clinical Trials of South Carolina, Charleston |
| Tennessee | Campbell Clinical Research, Franklin |
| Texas | FutureSearch Trials of Neurology, Austin
FutureSearch Trials of Dallas, Dallas
Mercury Clinical Research Inc. - Houston Neurology Associates, Houston
SFF Medical Research Group LLC, Houston |
| Virginia | MedStar Health: Headache Center at McLean, McLean |
| West Virginia | Vaught Neurological Services, Crab Orchard |
Conditions
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.