Impact of rTMS on Abnormal Cortical fMRI in Patients With Dystonia

Inclusion Criteria:

* Male or female
* 18 and 80 years of age.
* Patients who manifest dystonia - sustained involuntary movement of the head, neck, trunk or limbs.
* The dystonia may be spontaneous or genetic, specifically DYT1 or DYT6 and then only those patients who are demonstrating dystonia. The patient/subject will have a normal neurological exam except for dystonia.

Exclusion Criteria:

* Heredodegenrative dystonia of the type DYT8,9 or 10.
* Past history of head trauma, stroke, epilepsy, demyelinating disease
* Hypertension in excess of 160mmHg systolic and 90mmHg diastolic
* Congestive heart failure
* Diabetes
* Past psychiatric conditions: e.g., depression
* Systemic metabolic disease: e.g., Wilson's disease, progressive neurodegenerative disease (like supranuclear palsy or corticobasal ganglionic degeneration)
* Magnetizable incorporated metal parts - like pacemakers
* History or diagnosis of Parkinson's disease
* Presence of myoclonus
* No previous surgery for dystonia
* Long term exposure to benzodiazepines, neuroleptics or anticonvulsants
* No botulinum toxin within 12 weeks of baseline assessment and fMRI.
* Moderate to severe cognitive impairment (judged by a minimental status of \<24.)