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Dystonia clinical trials recruiting in the U.S.

21 studies for Dystonia are recruiting participants at sites across the United States.

Dystonia is a movement disorder. It causes involuntary, often painful, contractions of your muscles. Learn about causes, symptoms, and what can help.

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Recently updated studies

DaxibotulinumtoxinA for Blepharospasm

RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 29, 2026 ยท NCT07489430

Dystonia Genotype-Phenotype Correlation

RecruitingObservational studyHealthy volunteers welcome
Ages 11 and older ยท All sexes ยท Updated Sep 23, 2026 ยท NCT03428009

A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia

RecruitingPhase 2
Ages 18 to 70 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07304089

Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia

RecruitingHealthy volunteers welcome
Ages 6 to 21 ยท All sexes ยท Updated Sep 11, 2026 ยท NCT07325175

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

RecruitingObservational study
All ages ยท All sexes ยท Updated Sep 3, 2026 ยท NCT03664609

Deep Brain Stimulation Surgery for Movement Disorders

Recruiting
Ages 18 to 99 ยท All sexes ยท Updated Sep 1, 2026 ยท NCT01581580

Physiological Brain Atlas Development

RecruitingObservational study
Ages 6 to 90 ยท All sexes ยท Updated Aug 26, 2026 ยท NCT00575081

Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy

RecruitingPhase 1
Ages 5 to 17 ยท All sexes ยท Updated Jun 24, 2026 ยท NCT06554288

Impact of rTMS on Abnormal Cortical fMRI in Patients With Dystonia

RecruitingEarly phase 1
Ages 18 to 80 ยท All sexes ยท Updated Jun 4, 2026 ยท NCT07626216

Cortical-Basal Ganglia Speech Networks

Recruiting
Ages 18 to 85 ยท All sexes ยท Updated Mar 25, 2026 ยท NCT04286308

A Multicenter Pediatric Deep Brain Stimulation Registry

RecruitingObservational study
Ages 0 to 18 ยท All sexes ยท Updated Mar 18, 2026 ยท NCT06585618

A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

RecruitingObservational study
Ages 0 to 18 ยท All sexes ยท Updated Mar 18, 2026 ยท NCT06585605

Sleep-specific DBS Therapy in Parkinson's Disease

Recruiting
Ages 21 and older ยท All sexes ยท Updated Mar 3, 2026 ยท NCT05962489

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

RecruitingObservational study
All ages ยท All sexes ยท Updated Jan 8, 2026 ยท NCT04071847

Brain Networks in Dystonia

RecruitingObservational studyHealthy volunteers welcome
Ages 21 to 80 ยท All sexes ยท Updated Dec 8, 2025 ยท NCT03042962

Imaging Genetics of Laryngeal Dystonia

RecruitingObservational study
All ages ยท All sexes ยท Updated Dec 2, 2025 ยท NCT03042975

Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor

Recruiting
Ages 18 to 80 ยท All sexes ยท Updated Dec 2, 2025 ยท NCT05150093

Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia

RecruitingHealthy volunteers welcome
All ages ยท All sexes ยท Updated Dec 2, 2025 ยท NCT05317390

Intrathecal Baclofen and Pediatric Dystonia

Recruiting
Up to age 17 ยท All sexes ยท Updated Jul 30, 2025 ยท NCT06606574

Effects of Exercise on Dystonia Pathophysiology

Recruiting
Ages 30 to 85 ยท All sexes ยท Updated Jul 28, 2025 ยท NCT05663840

Clinical Outcomes for Deep Brain Stimulation

RecruitingObservational study
All ages ยท All sexes ยท Updated Jun 20, 2019 ยท NCT03992625

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.