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LIFU for Chronic Pain and Generalized Anxiety Disorder

Recruiting

Accelerated Low-Intensity Focused Ultrasound (LIFU) for Chronic Pain and Generalized Anxiety Disorder: A Proof-of-Concept Case Series

Who can join

Ages 18 to 65 · All sexes

Full eligibility criteria
Inclusion Criteria:

* GAD Symptoms - GAD-7 score \>= 10, OASIS score \>= 8, or PSWQ score \>= 45. OR Chronic pain symptoms - moderate to severe pain, present for at least 3 months.

Exclusion Criteria:

* Claustrophobia
* Contraindications to MRI or CT
* Active medical disorder with CNS effects
* History of neurologic disorder
* History of head injury with LOC \> 10 minutes
* Active drug or alcohol dependence

About the study

A proof of concept case study to investigate accelerated LIFU protocol in chronic pain and anxiety populations.

What is being tested

Sponsor: Virginia Polytechnic Institute and State University · Participants: 10 · Started: 2026-12

Contact the study team

Official record on ClinicalTrials.gov — NCT07686354

Locations in the U.S.

VirginiaFralin Biomedical Research Institute at VTC, Roanoke

Conditions

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.