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Home-Based Walking for Thinking Skills in Persons With TBI

RecruitingEarly phase 1

Safety and Feasibility of Remote Walking Exercise for Cognitive Improvement in Persons With TBI

Who can join

Ages 18 to 65 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Definitive TBI diagnosis at least 1 year prior, verified by medical records
* Self-report problems with thinking skills since the TBI diagnosis (e.g., processing information, learning or remembering, organizing, multitasking)
* Between the ages of 18 and 65
* Access to internet and email
* Fluent in English
* Can walk at a brisk pace without using an assistive device
* Not fallen due to mobility issues from their TBI in the past 6 months
* Do not currently meet public health guidelines for physical activity
* Have problems with thinking performance

Exclusion Criteria:

* I currently have uncontrolled major depression
* I have a history of schizophrenia, bipolar disorder I or II, or substance-abuse disorders
* I am regularly taking medications that can affect my thinking, such as antipsychotics or benzodiazepines. Study staff will review my medications to determine if I am taking any that would make me ineligible for this study
* I have known/diagnosed cardiovascular disease including uncontrolled hypertension, diabetes, or kidney disease
* I am unable to make everyday decisions on my own

About the study

The purpose of this research study is to investigate the effects of a home-based 3-month long walking exercise program on cognitive (thinking) performance in persons with TBI. As a participant, you will complete this 3-month exercise program now or after a 3-month wait period.

What is being tested

Sponsor: Kessler Foundation · Participants: 40 · Started: Apr 15, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07733284

Locations in the U.S.

New JerseyKessler Foundation, East Hanover

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.