Gestational Response, Outcomes, and Weight After GLP-1 Use
Who can join
Ages 18 to 45 · Women · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Adult women * Less than or equal to 20 weeks gestation at first visit * English speaking Exclusion Criteria: * \<18 years at time of initial visit * Type 2 diabetes * History of bariatric surgery * Multiple gestation * Cannot consent for themselves * Cannot read and speak English * Incarcerated
About the study
The goal of this observational study is to learn if using GLP-1RA medications for weight loss before pregnancy influences gestational weight gain and pregnancy outcomes. The main aims of the study are to:
* Compare gestational weight gain between women with preconception GLP-1RA exposure and those without exposure. * Compare obstetrical outcomes between women with preconception GLP-1RA exposure and those without exposure.
Researchers will compare pregnant women with a history of GLP-1RA use to pregnant women who have not used a GLP-1RA to compare differences.
Participants will be asked to complete questionnaires at multiple timepoints during and after pregnancy that ask questions about medication history, thoughts and feelings around food, etc.
Sponsor: University of Kansas Medical Center · Participants: 400 · Started: Apr 13, 2026
Contact the study team
- Molly Fain · Phone: 913-588-5478
Official record on ClinicalTrials.gov — NCT07743567
Locations in the U.S.
| Kansas | University of Kansas Medical Center, Kansas City |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.