Optimizing Lymphatic Pumping for Influenza Vaccine Responses in Vulnerable Populations
RecruitingHealthy volunteers welcome
Who can join
Ages 18 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Willing to receive OMT * Willing to receive influenza vaccine * Older than 18 years of age Exclusion Criteria: * Younger than 18 years of age * Pregnancy or lactation * Unwilling to receive the influenza vaccine * Unwilling to receive OMT * Open wounds * Bone fractures * Moderate to severe osteoporosis * Severe COPD * Current/active infections * Mononucleosis infection within past 6 months * Liver cirrhosis * Cancer or metastatic disease * History of DVT, PE, or blood clotting disorder * Individuals taking blood thinning medications, except aspirin * Having a pacemaker or other thoracic medical devices
About the study
The investigators are studying if a specific osteopathic manipulative treatment protocol can improve the immune response (antibody titers) to seasonal influenza vaccination in vulnerable populations, including patients with advanced age and/or adiposity.
What is being tested
- Osteopathic Manipulation (other)
- Osteopathic manipulation (other)
- Sham (other)
Sponsor: Lake Erie College of Osteopathic Medicine · Participants: 50 · Started: 2026-09
Contact the study team
- David Duriancik, Ph.D. · Phone: 814-860-5139
- Irv Freeman, J.D., Ph.D. · Phone: 724-552-2870
Official record on ClinicalTrials.gov — NCT07786467
Locations in the U.S.
| Pennsylvania | Plaza 38 Medical Offices, Erie |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.