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Flu clinical trials recruiting in the U.S.
47 studies for Flu are recruiting participants at sites across the United States.
The flu can cause serious illness in people over 65, babies, and people with certain chronic illnesses. The best way to prevent the flu is to get a vaccine.
Cities with the most studies
- Atlanta, GA10 studies
- Washington, DC8 studies
- St. Louis, MO7 studies
- Houston, TX7 studies
- Chicago, IL6 studies
- Charlottesville, VA6 studies
- Hialeah, FL6 studies
- Baltimore, MD6 studies
- Tucson, AZ5 studies
- Overland Park, KS5 studies
- San Diego, CA5 studies
- Miami, FL5 studies
- Durham, NC4 studies
- Seattle, WA4 studies
- Winston-Salem, NC4 studies
- Philadelphia, PA4 studies
- Salt Lake City, UT4 studies
- Richmond, VA3 studies
- Portland, OR3 studies
- Columbus, OH3 studies
- West Palm Beach, FL3 studies
- Deltona, FL3 studies
- Glendale, AZ3 studies
- Dallas, TX3 studies
- Rochester, NY3 studies
- Anniston, AL3 studies
- Tempe, AZ3 studies
- Meridian, ID3 studies
- Spartanburg, SC3 studies
- Torrance, CA3 studies
- Kansas City, MO3 studies
- Pittsburgh, PA3 studies
By state
- Alabama6 studies
- Arizona6 studies
- Arkansas3 studies
- California14 studies
- Colorado4 studies
- Connecticut4 studies
- Florida9 studies
- Georgia11 studies
- Idaho5 studies
- Illinois8 studies
- Indiana4 studies
- Kansas6 studies
- Kentucky3 studies
- Louisiana5 studies
- Maryland12 studies
- Massachusetts3 studies
- Michigan4 studies
- Minnesota4 studies
- Missouri10 studies
- Nevada3 studies
- New York7 studies
- North Carolina6 studies
- Ohio7 studies
- Oklahoma3 studies
- Oregon3 studies
- Pennsylvania9 studies
- South Carolina5 studies
- Tennessee4 studies
- Texas11 studies
- Utah4 studies
- Virginia7 studies
- Washington4 studies
Recently updated studies
A Study to Evaluate the Safety and Efficacy of MK-1406/CD388 for Prevention of Influenza (MK-1406-005/CD388.SQ.3.06)
RecruitingPhase 3
Ages 12 and older · All sexes · Updated Nov 13, 2026 · NCT07159763A Study of Updated mRNA Seasonal Influenza Vaccines
RecruitingPhase 4Healthy volunteers welcome
Ages 65 and older · All sexes · Updated Nov 13, 2026 · NCT07884175First-in-Human Study of VNT-101: Safety, Tolerability, and Pharmacokinetics
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 59 · All sexes · Updated Nov 13, 2026 · NCT07169318pH1N1 Blinded Challenge Study
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Nov 13, 2026 · NCT07110532BPL-1357 Against H1N1 Influenza Virus Challenge
RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Nov 13, 2026 · NCT07215858Screening for LID Clinical Studies Unit Healthy Volunteer Protocols
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Nov 12, 2026 · NCT01386424Systems Investigation of Vaccine Responses in Aging and Frailty
RecruitingPhase 2Healthy volunteers welcome
Ages 21 and older · All sexes · Updated Nov 10, 2026 · NCT05291676A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in Healthy Children
RecruitingPhase 1Healthy volunteers welcome
Ages 9 to 17 · All sexes · Updated Nov 5, 2026 · NCT07870330Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
RecruitingPhase 3
28 Days · All sexes · Updated Nov 4, 2026 · NCT02735707A Trial to Evaluate the Effect of CD388/MK1406 on the Immunogenicity of Fluzone® HD Vaccine (CD388.SQ.1.08/MK-1406-007)
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 49 · All sexes · Updated Nov 4, 2026 · NCT07300085Age-Associated Differences in Germinal Center Responses to Influenza and Rabies Vaccination in Humans
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07914673Comparative Immunogenicity of Respiratory Virus Vaccines (CIRV2) Study
RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 79 · All sexes · Updated Nov 2, 2026 · NCT07287137Clinical Outcomes and Pharmacotherapy Effectiveness in the VA Health Care System (COPE-VA)
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT06160128Impact of Egg-Based and Cell-Based Vaccine Platforms on Immune Responses to Repeated Influenza Vaccination
RecruitingPhase 4Healthy volunteers welcomeMentions payment for participants
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT07910266Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT05624450High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients
RecruitingPhase 2
Ages 3 to 17 · All sexes · Updated Oct 28, 2026 · NCT05947071Light-based Immunomodulation for Guarding Against Human Respiratory Tract Infections
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT07610967A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts
RecruitingPhase 3
3 Weeks – 11 Years · All sexes · Updated Oct 23, 2026 · NCT06094010High vs. Standard Dose Influenza Vaccines in Lung Transplant (Repeater)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT07192458A Study to Evaluate the Immune Response and Safety of a Vaccine Against Influenza in Adults 18-64 Years of Age
RecruitingPhase 3Healthy volunteers welcome
Ages 18 to 64 · All sexes · Updated Oct 9, 2026 · NCT07851246Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Oct 9, 2026 · NCT07149428Optimizing Lymphatic Pumping for Influenza Vaccine Responses in Vulnerable Populations
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07786467A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
RecruitingPhase 3Healthy volunteers welcome
Ages 65 and older · All sexes · Updated Sep 18, 2026 · NCT07805707Study to Assess Safety and Immunogenicity of an Egg-based H5N8 Influenza Vaccine at Multiple Dose Levels Adjuvanted With Matrix-M in Healthy Participants 18 Years of Age and Above.
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07779408Observational Digital Biomarker Discovery in Respiratory Virus Challenge Studies
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 9, 2026 · NCT04772170From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.