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Flu clinical trials recruiting in the U.S.
39 studies for Flu are recruiting participants at sites across the United States.
The flu can cause serious illness in people over 65, babies, and people with certain chronic illnesses. The best way to prevent the flu is to get a vaccine.
Cities with the most studies
- Atlanta, GA9 studies
- Washington, DC7 studies
- Chicago, IL5 studies
- Philadelphia, PA5 studies
- Charlottesville, VA5 studies
- Baltimore, MD4 studies
- Salt Lake City, UT4 studies
- Hialeah, FL4 studies
- Houston, TX4 studies
- Seattle, WA4 studies
- Durham, NC4 studies
- St. Louis, MO4 studies
- Kansas City, MO3 studies
- Rochester, NY3 studies
- Winston-Salem, NC3 studies
- Columbus, OH3 studies
- Portland, OR3 studies
- Miami, FL3 studies
- Torrance, CA3 studies
- San Diego, CA3 studies
By state
- Alabama5 studies
- Arizona3 studies
- Arkansas3 studies
- California10 studies
- Connecticut3 studies
- Florida7 studies
- Georgia10 studies
- Idaho3 studies
- Illinois7 studies
- Kansas3 studies
- Louisiana4 studies
- Maryland9 studies
- Michigan3 studies
- Missouri6 studies
- New York5 studies
- North Carolina5 studies
- Ohio5 studies
- Oregon3 studies
- Pennsylvania8 studies
- South Carolina3 studies
- Tennessee4 studies
- Texas8 studies
- Utah4 studies
- Virginia5 studies
- Washington4 studies
Recently updated studies
BPL-1357 Against H1N1 Influenza Virus Challenge
RecruitingPhase 2Healthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Sep 28, 2026 · NCT07215858pH1N1 Blinded Challenge Study
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 55 · All sexes · Updated Sep 25, 2026 · NCT07110532A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts
RecruitingPhase 3
3 Weeks – 11 Years · All sexes · Updated Sep 24, 2026 · NCT06094010High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients
RecruitingPhase 2
Ages 3 to 17 · All sexes · Updated Sep 24, 2026 · NCT05947071Optimizing Lymphatic Pumping for Influenza Vaccine Responses in Vulnerable Populations
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07786467Screening for LID Clinical Studies Unit Healthy Volunteer Protocols
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 22, 2026 · NCT01386424A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
RecruitingPhase 3Healthy volunteers welcome
Ages 65 and older · All sexes · Updated Sep 18, 2026 · NCT07805707Evaluating the Dose, Safety, Tolerability, and Immunogenicity of Mosaic Hexavalent Influenza Vaccine VRCFLUMOS0116-00-VP (FluMos-v2) With and Without ALFQ Adjuvant in Healthy Adults
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 50 · All sexes · Updated Sep 15, 2026 · NCT06863142Study to Assess Safety and Immunogenicity of an Egg-based H5N8 Influenza Vaccine at Multiple Dose Levels Adjuvanted With Matrix-M in Healthy Participants 18 Years of Age and Above.
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07779408Observational Digital Biomarker Discovery in Respiratory Virus Challenge Studies
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 9, 2026 · NCT04772170Clinical Outcomes and Pharmacotherapy Effectiveness in the VA Health Care System (COPE-VA)
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06160128Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05624450Dime La VerDAD: Verify, Debunk, and Disseminate
RecruitingHealthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Aug 26, 2026 · NCT06417762Respiratory Virus Sampling and Repository
RecruitingObservational study
Ages 3 and older · All sexes · Updated Aug 17, 2026 · NCT05266222Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years
RecruitingObservational studyHealthy volunteers welcome
Ages 65 and older · All sexes · Updated Aug 5, 2026 · NCT06029933Baloxavir and Oseltamivir for the Treatment of Severe Influenza Infection in Immunocompromised Patients
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Jul 16, 2026 · NCT04712539The Effects of Endotracheal Suctioning on Pain and Serum Markers
Recruiting
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06692400A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults
RecruitingPhase 1
Ages 65 to 85 · All sexes · Updated Jun 30, 2026 · NCT07464314Flu Infection at UPHS
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06807840First-in-Human Study of VNT-101: Safety, Tolerability, and Pharmacokinetics
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 59 · All sexes · Updated May 11, 2026 · NCT07169318A Study to Learn About mRNA Vaccines Against Influenza in Adults
RecruitingPhase 2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07431853Woodsmoke Exposure, Influenza Infection, and Nasal Immunity
RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 49 · All sexes · Updated Apr 30, 2026 · NCT06841913H5N1 Milk Detection Study
RecruitingHealthy volunteers welcome
Ages 18 to 64 · All sexes · Updated Apr 15, 2026 · NCT06850298The INFLUENTIAL Trial- Evaluation of National Inpatient Influenza Vaccination Program
RecruitingHealthy volunteers welcome
6 Months – 99 Years · All sexes · Updated Apr 8, 2026 · NCT05832307MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies
RecruitingPhase 2
Up to age 60 · All sexes · Updated Apr 6, 2026 · NCT05735717From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.