Imaging Assessment of Swallowing and Speech Muscles in Inclusion Body Myositis

Inclusion Criteria:

* Participants must have a confirmed diagnosis of inclusion body myositis (IBM), amyotrophic lateral sclerosis (ALS), primary lateral sclerosis (PLS), or myopathy in accordance with the respective diagnostic criteria.
* Participants with disease must have clinically relevant laboratory testing for disease biomarkers (e.g., Creatine Kinase (CK), Comprehensive Metabolic Panel (CMP), Complete Blood Count (CBC)) within the last 12 months.
* Participants must be able to remain supine for 30 minutes or longer and cannot have significant breathing difficulties.
* Healthy controls must not have any neuromuscular disease.

Exclusion Criteria:

* Unable or unwilling to provide written informed consent.
* Medical history or clinically significant physical examination or laboratory results that, in the opinion of the investigator, would render the participant unsuitable for the study.
* Participants who are unlikely to comply with the study protocol or, in the opinion of the investigator, would not be a suitable candidate for participation in the study.
* Patients with IBM, ALS, or myopathy who have another known neuromuscular condition with known bulbar involvement.
* Any patient who has undergone a procedure for dysphagia, including myotomy, dilatation, or Botox.