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Addressing Spasticity and Motor Function With Epidural Spinal Cord Stimulation
Pilot Study: Addressing Spasticity and Motor Function With Epidural Spinal Cord Stimulation
Who can join
Ages 22 and older · All sexes
Full eligibility criteria
Inclusion Criteria: 1. At least 22 years of age 2. Post 1 year non-progressive SCI 3. Stable medical condition (cleared by the study physician and do not have any medical conditions that would interfere with study procedures) 4. Diagnosed with and treated for severe spasticity at least 6 months ago Exclusion Criteria: 1. ventilator dependent 2. untreated painful musculoskeletal dysfunction, fracture or pressure injury 3. untreated psychiatric disorder or ongoing drug abuse 4. cardiac, respiratory, bladder, renal or other untreated medical disorder unrelated to SCI 5. Botulinum toxin injections (such as Botox) or other injections to manage spasms (such as phenol or alcohol) in any muscle or bladder less than 6 months prior to implant 6. colostomy bag, urostomy 7. Any active implantable devices or implanted pump (such as a baclofen pump, pain pump, etc.) 8. pregnant at the time of enrollment or planning to become pregnant during the time course of the study 9. Contraindications to MRI imaging (e.g., pacemaker, metallic foreign body, aneurysm clip) 10. Imaging findings that determine the area of spine the stimulation device would be implanted is not suitable for surgery (such as implanted hardware interference or additional deterioration/injury of spinal cord at or below the region) 11. Severe muscle contractures 12. unable to operate a touch screen
About the study
The purpose of this study is to investigate treating severe spasticity in persons with spinal cord injury by implanting a device in the body that delivers electrical stimulation around the spinal cord (spinal cord epidural stimulation). This study will be closely monitoring a program designed to treat spasticity using an epidural stimulator to better understand its effects on spasticity and voluntary movement.
What is being tested
- Epidural implant stimulation device (device)
Sponsor: Kessler Foundation · Participants: 8 · Started: Oct 1, 2026
Contact the study team
- Research Manager · Phone: 973-324-3557
Official record on ClinicalTrials.gov — NCT07890558
Locations in the U.S.
| New Jersey | Kessler Foundation, West Orange |
Conditions
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.