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Muscle Spasticity clinical trials recruiting in the U.S.
25 studies for Muscle Spasticity are recruiting participants at sites across the United States.
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Recently updated studies
Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT05094362Outcomes of Neurosurgical Tone Management
RecruitingObservational study
Ages 6 to 25 · All sexes · Updated Sep 14, 2026 · NCT07817745A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Sep 9, 2026 · NCT06782490Robot Aided Rehabilitation - Multi-joint Evaluations
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Sep 1, 2026 · NCT02359812Robot Aided Rehabilitation - Intervention
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 1, 2026 · NCT02359253Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT07639060Effect of Neural Constraints on Movement in Stroke
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Aug 18, 2026 · NCT06666673Dorsal Root Electrical Stimulation in Children With Cerebral Palsy
Recruiting
Ages 3 to 14 · All sexes · Updated Aug 11, 2026 · NCT07715006A Pilot Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368, a FAAH/MAGL Inhibitor, in Participants With Post-Stroke Spasticity (The STIPS Study)
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Jul 29, 2026 · NCT07704840A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.
RecruitingPhase 1/2
Ages 18 to 70 · All sexes · Updated Jul 28, 2026 · NCT04752774Melpida: Recombinant Adeno-associated Virus (Serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)
RecruitingPhase 1/2
4 Months – 10 Years · All sexes · Updated Jul 8, 2026 · NCT05518188Functional Balance Intervention in Multiple Sclerosis
Recruiting
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT06341023Trial to Test the Effectiveness of Vibrotactile Stimulation for Lower Limb Spasticity
Recruiting
Ages 18 to 85 · All sexes · Updated Jun 17, 2026 · NCT07447934Spasticity in SCI Following Acute Intermittent Hypoxia
Recruiting
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT07583498Spinal Cord Stimulation for Children With Cerebral Palsy
RecruitingHealthy volunteers welcome
Ages 5 to 17 · All sexes · Updated Apr 7, 2026 · NCT07516067Shockwave for Elbow and Wrist Spasticity in People With Spinal Cord Injury
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT07501429Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)
RecruitingObservational study
1 Month – 30 Years · All sexes · Updated Mar 18, 2026 · NCT05354622Leg Stretching Using an Exoskeleton on Demand for People With Spasticity
Recruiting
Ages 18 and older · All sexes · Updated Feb 23, 2026 · NCT05926596Exoskeleton and Spinal Cord Stimulation for SCI
Recruiting
Ages 18 to 65 · All sexes · Updated Jan 14, 2026 · NCT03096197Orthosis to Improve Trunk Control in Infants Age 6-18 Months
RecruitingObservational study
6 Months – 18 Months · All sexes · Updated Jan 14, 2026 · NCT06027580Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy
Recruiting
Ages 16 and older · All sexes · Updated Dec 19, 2025 · NCT06070233Intrathecal Baclofen and Pediatric Dystonia
Recruiting
Up to age 17 · All sexes · Updated Jul 30, 2025 · NCT06606574Dry Needling in Multiple Sclerosis
Recruiting
Ages 18 to 64 · All sexes · Updated Jun 11, 2025 · NCT06394310Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
RecruitingObservational study
All ages · All sexes · Updated May 29, 2025 · NCT01793168The Effect of Cupping on Spasticity and Function of the Lower Extremity During Rehabilitation After Stroke
Recruiting
Ages 30 to 80 · All sexes · Updated Dec 13, 2024 · NCT06653855From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.