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Bladder Cancer clinical trials in Florida

38 studies for Bladder Cancer are looking for participants at sites in Florida.

Cities in Florida

Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

  • UF Health Cancer Institute - Gainesville, Gainesville
  • Mayo Clinic in Florida, Jacksonville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07000084

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • Schulze Family Foundation Cancer Clinic - Bonita Health Center, Bonita Springs
  • Morton Plant Hospital, Clearwater
  • and 11 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

  • Mount Sinai Comprehensive Cancer Center at Aventura, Aventura
  • UF Health Cancer Institute - Gainesville, Gainesville
  • Mount Sinai Medical Center, Miami Beach
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06770582

A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

  • Florida Cancer Specialists & Research Institute - Fort Myers Cancer Center - Gladiolus, Fort Myers
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06760819

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

  • Urological Research Network ( Site 0133), Hialeah
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06833073

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • AdventHealth Medical Group Oncology Research at Celebration, Kissimmee
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

  • Mayo Clinic in Florida, Jacksonville
  • Moffitt Cancer Center at SouthShore, Ruskin
  • Moffitt Cancer Center-International Plaza, Tampa
  • and 3 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07061964

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

  • Holy Cross Hospital, Fort Lauderdale
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

  • Moffitt Cancer Center at SouthShore, Ruskin
  • Moffitt Cancer Center - International Plaza, Tampa
  • Moffitt Cancer Center - McKinley Campus, Tampa
  • and 3 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07206225

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

  • BRCR Global-Coral Springs, Coral Springs
  • Mayo Clinic Florida, Jacksonville
  • Sarah Cannon Research Institute at Florida Cancer Specialists, Orlando
  • and 1 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

DESTINY-PANTUMOUR04

  • Research Site, Coral Springs
  • Research Site, St. Petersburg
  • Research Site, West Palm Beach
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

  • AdventHealth Orlando, Orlando
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

Personalized Cancer Vaccine (PCV) Strategy in Patients With Solid Tumors and Molecular Residual Disease

  • AdventHealth, Orlando
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06529822

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

  • Sylvester Comprehensive Cancer Center - Miami, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • Memorial Healthcare System, Hollywood
  • The Oncology Institute of Hope & Innovation, Lakeland
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Exploration of Novel AI-enabled Blue Light Enhanced Cystoscopy

  • Moffitt Cancer Center, Tampa
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07144319

Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

  • University of Florida, Gainesville
  • Mayo Clinic Florida, Jacksonville
  • Advanced Urology Institute (Solaris), Largo
  • and 1 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06567743

Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

  • Mayo Clinic, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT05951179

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

  • Advent Health, Orlando
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05614739

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

  • UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables
  • UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach
  • UM Sylvester Comprehensive Cancer Center at Doral, Doral
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07097142

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

  • AdventHealth Celebration, Celebration
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

  • University of Florida, Jacksonville
  • Sylvester Comprehensive Cancer Center / University of Miami Hospital and Clinics, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT04752722

Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

  • H. Lee Moffitt Cancer Center & Research Institute, Tampa
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07225127

Study Investigating Intravesical HDAC Inhibition to Improve Response to Immuno-Oncology Agents

  • Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT06963346

Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy

  • Miami Cancer Institute at Baptist Health, Inc., Miami
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT07106762

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

  • University of Miami Hospital and Clinics, Miami
RecruitingPhase 2
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

  • Florida Cancer Specialists, Bonita Springs
  • Florida Cancer Specialists, Bradenton
  • Florida Cancer Specialists, Bradenton
  • and 14 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT04879329

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

  • American Oncology Partners, PA. a Florida professional service corporation, d/b/a Vista Oncology, Fort Myers
  • Florida Cancer Specialists & Research Institute, LLC, Fort Myers
  • Memorial Cancer Institute, Hollywood
  • and 4 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.

  • Advanced Urology Institute - Daytona Beach, Daytona Beach
Recruiting
Ages 18 to 88 · All sexes · Updated Jul 2, 2026 · NCT06394869

Integrated Cancer Repository for Cancer Research

  • Florida Hospital Memorial Medical Center, Daytona Beach
  • Florida Hospital DeLand, DeLand
  • Florida Hospital FISH, Orange City
  • and 2 more
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE Trial

  • Mayo Clinic in Florida, Jacksonville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT06704191

Intravesical Gemcitabine and Docetaxel for Low Grade Intermediate Risk Bladder Cancer

  • University of Florida, Gainesville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 11, 2026 · NCT06488222

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

  • Florida Cancer Specialists-Lake Nona, Orlando
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

  • University of Miami - Sylvester Comprehensive Cancer Center, Miami
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

  • Miami Cancer Institute, Miami
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Jacksonville
  • Massive Bio SYNERGY-AI site, Miami
  • Massive Bio SYNERGY-AI site, Tampa
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Beta-only IL-2 ImmunoTherapY Study

  • Boca Raton Regional Hospital, Boca Raton
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05086692

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.