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Bladder Cancer clinical trials recruiting in the U.S.

140 studies for Bladder Cancer are recruiting participants at sites across the United States.

Bladder cancer symptoms range from lower back pain to blood in your urine. Read about important risk factors and find a list of treatments available

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Recently updated studies

A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)

RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07222488

Evaluation for NCI Surgery Branch Clinical Research Protocols

RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT00001823

Home Intravenous Fluid Infusion After Undergoing Radical Cystectomy

Recruiting
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07225205

A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07419295

Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease

RecruitingObservational studyHealthy volunteers welcome
Ages 2 and older · All sexes · Updated Nov 9, 2026 · NCT00026884

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Nov 6, 2026 · NCT06995898

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07090499

A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07206225

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06465069

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Nov 4, 2026 · NCT05366881

Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy

Recruiting
Ages 18 and older · Men · Updated Nov 4, 2026 · NCT05792722

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Nov 4, 2026 · NCT05334069

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT05614739

Study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in Patients With Solid Tumors

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07660055

Outcomes of High-risk Non-muscle Invasive Bladder Cancer Treated With Blue Light Resection

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT06525571

Risk-Enabled Therapy After Initiating EV/Pembro for Bladder Cancer

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT07908979

Study Investigating Intravesical HDAC Inhibition to Improve Response to Immuno-Oncology Agents

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT06963346

Exploration of Novel AI-enabled Blue Light Enhanced Cystoscopy

RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT07144319

En-bloc Transurethral Resection of Bladder Tumor (En-bloc TURBT) Specimens Using a Redesigned Surgical Resectoscope Device

RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Oct 29, 2026 · NCT04235764

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

RecruitingPhase 2
Ages 18 to 120 · All sexes · Updated Oct 29, 2026 · NCT06503146

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.