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Cardiovascular Disease clinical trials in Minnesota
31 studies for Cardiovascular Disease are looking for participants at sites in Minnesota.
Cities in Minnesota
ELEVATE-HFpEF Clinical Study
- M Health Fairview University of Minnesota Medical Center - East Bank, Minneapolis
Recruiting
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
- Mayo Clinic, Rochester
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Oct 1, 2026 · NCT07137338A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
- Minneapolis Heart Institute, Minneapolis
Recruiting
Ages 18 to 85 · All sexes · Updated Sep 28, 2026 · NCT07286578Obstructive Sleep Apnea Among Somali-Americans
- Mayo Clinic, Rochester
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT04124848Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
- Aspirus Saint Luke's Hospital, Duluth
- Essentia Health-SMMC, Duluth
- JAVARA Inc, - Mankato Clinic, Mankato
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06909565Product Surveillance Registry
- Coon Rapids
- Minneapolis
- Robbinsdale
- and 1 more
RecruitingObservational study
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
- Clinical Trial Site, Richfield
- Clinical Trial Site, Saint Cloud
- Clinical Trial Site, Saint Paul
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109Zenith® Fenestrated+ Clinical Study
- Mayo Clinic, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
- Abbott Northwestern Hospital, Minneapolis
Recruiting
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
- Abbott Northwestern Hospital, Minneapolis
- University of Minnesota, Minneapolis
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)
- Mayo Clinic, Rochester
RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07601425Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
- Essentia Health, Duluth
- Mayo Clinic, Rochester
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma
- Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis
RecruitingObservational study
Ages 7 and older · All sexes · Updated Aug 25, 2026 · NCT05705531A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
- Research Site, Duluth
- Research Site, Minneapolis
- Research Site, Minneapolis
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
- Saint Marys Medical Center, Duluth
- Health East Cancer Care, Maplewood
- University of Minnesota, Minneapolis
- and 2 more
RecruitingPhase 3
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012VDyne Transcatheter Tricuspid Valve Replacement Study to Evaluate Safety and Clinical Efficacy in Patients With Symptomatic Severe Tricuspid Valve Regurgitation (TRIVITA Pivotal Trial)
- Minneapolis Heart Institute Foundation, Minneapolis
Recruiting
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07516444Global Paradise System US Post Approval Study
- Metropolitan Heart & Vascular Institute, Coon Rapids
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06297291COMPARE-VENT Feasibility Pilot Study
- Mayo Clinic, 1216 Second Street SW, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07656259The TRICURE EFS Study
- Minneapolis Heart Institute Foundation, Minneapolis
Recruiting
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06506942PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- University of Minnesota, Minneapolis
- Centra Care Heart Center, Saint Cloud
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Minneapolis Heart Institute, Minneapolis
- Mayo Clinic, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195Mayo AVC Registry and Biobank
- Mayo Clinic, Rochester
RecruitingObservational studyHealthy volunteers welcome
All ages · All sexes · Updated Apr 27, 2026 · NCT03049254The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
- CentraCare Heart and Vascular, Saint Cloud
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
- Mayo Clinic, Rochester
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06271577CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes
- Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT05931276CVD/PH and Voice Characteristics
- Mayo Clinic, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 30, 2025 · NCT07311044A Study of Mayo Clinic CV Research Heart & Voice Study
- Mayo Clinic in Rochester, Rochester
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 5, 2025 · NCT07224685Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure
- University of Minnesota, Minneapolis
RecruitingEarly phase 1
Ages 60 and older · All sexes · Updated Oct 3, 2025 · NCT06507657Techquity by FAITH!
- Mayo Clinic in Rochester, Rochester
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 26, 2025 · NCT06187077MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
- Metropolitan Heart and Vascular Institute, Coon Rapids
- Minneapolis Heart Institute Foundation, Minneapolis
Recruiting
Ages 18 to 110 · All sexes · Updated Feb 25, 2025 · NCT05908331PARTNER 3 Trial - Aortic Valve-in-Valve
- Mayo Clinic, Rochester
Recruiting
All ages · All sexes · Updated May 10, 2024 · NCT03003299From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.