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Cholesterol clinical trials recruiting in the U.S.
23 studies for Cholesterol are recruiting participants at sites across the United States.
Your body needs some cholesterol, but too much can raise your risk of heart disease. Know the types (HDL and LDL), and how to lower high cholesterol.
Cities with the most studies
- Washington, DC7 studies
- Hialeah, FL6 studies
- Jacksonville, FL5 studies
- Durham, NC4 studies
- Deltona, FL4 studies
- Houston, TX4 studies
- Richmond, VA4 studies
- Clearwater, FL4 studies
- Orlando, FL3 studies
- Anderson, SC3 studies
- Evansville, IN3 studies
- Johns Creek, GA3 studies
- Wilmington, NC3 studies
- Dallas, TX3 studies
- Winston-Salem, NC3 studies
- New York City, NY3 studies
- Salt Lake City, UT3 studies
- St. Louis, MO3 studies
- Wichita, KS3 studies
- Chicago, IL3 studies
- Alexandria, VA3 studies
By state
- Alabama5 studies
- Arizona4 studies
- California7 studies
- Florida8 studies
- Georgia5 studies
- Illinois4 studies
- Indiana4 studies
- Kansas3 studies
- Kentucky3 studies
- Louisiana5 studies
- Maryland5 studies
- Missouri4 studies
- New York5 studies
- North Carolina8 studies
- Ohio3 studies
- Oklahoma3 studies
- Oregon3 studies
- Pennsylvania4 studies
- South Carolina5 studies
- Tennessee4 studies
- Texas7 studies
- Utah3 studies
- Virginia5 studies
- Washington3 studies
Recently updated studies
A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Rosuvastatin on LDL-C in Patients With Hypercholesterolaemia
RecruitingPhase 3
Ages 18 to 130 ยท All sexes ยท Updated Oct 5, 2026 ยท NCT07619118Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
RecruitingPhase 4
Ages 18 and older ยท All sexes ยท Updated Oct 5, 2026 ยท NCT06909565Causes and Natural History of Dyslipidemias
RecruitingObservational study
Ages 2 to 100 ยท All sexes ยท Updated Oct 2, 2026 ยท NCT00353782Computerized Decision Support for Identification and Management of Familial Hypercholesterolemia
Recruiting
All ages ยท All sexes ยท Updated Sep 29, 2026 ยท NCT06743659A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
RecruitingPhase 1
Ages 18 to 75 ยท All sexes ยท Updated Sep 18, 2026 ยท NCT07491172A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Laroprovstat, Rosuvastatin and Placebo on LDL-C in LLT-naรฏve Patients.
RecruitingPhase 3
Ages 18 to 130 ยท All sexes ยท Updated Sep 10, 2026 ยท NCT07619131Arizona CEAL: Linking Social Care With Healthcare Systems to Address SDOH
RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Sep 2, 2026 ยท NCT07799961A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Jul 30, 2026 ยท NCT07610278Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
RecruitingPhase 3
Ages 2 to 11 ยท All sexes ยท Updated Jul 24, 2026 ยท NCT06597006A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
RecruitingPhase 2
Ages 18 to 80 ยท All sexes ยท Updated Jul 22, 2026 ยท NCT07477704Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia
RecruitingPhase 1
Ages 18 to 70 ยท All sexes ยท Updated Jul 17, 2026 ยท NCT06451770Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food
Recruiting
Ages 18 to 60 ยท All sexes ยท Updated Jul 16, 2026 ยท NCT06988462Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
RecruitingPhase 3
Ages 6 to 11 ยท All sexes ยท Updated May 15, 2026 ยท NCT06597019Assessing the Effects of Corn and Avocado Oils on the Cardiometabolic Risk Factor Profile
RecruitingHealthy volunteers welcome
Ages 18 to 74 ยท All sexes ยท Updated Apr 17, 2026 ยท NCT07514663Pharmacogenomic Informed Statin Prescribing
Recruiting
Ages 40 to 75 ยท All sexes ยท Updated Apr 13, 2026 ยท NCT06568601Mechanism of Ketogenic Diet-Induced Hypercholesterolemia
RecruitingHealthy volunteers welcome
Ages 18 to 39 ยท All sexes ยท Updated Mar 23, 2026 ยท NCT06894004Multicomponent Intervention Study- Blood Donors With High Cholesterol
Recruiting
Ages 18 to 75 ยท All sexes ยท Updated Mar 17, 2026 ยท NCT05693701Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial
RecruitingPhase 2
Ages 40 to 75 ยท All sexes ยท Updated Feb 27, 2026 ยท NCT06488105Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jan 29, 2026 ยท NCT06374277FELLAShip to Better Health
Recruiting
Ages 18 and older ยท Men ยท Updated Jan 22, 2026 ยท NCT07220213HoFH, the International Clinical Collaborators Registry
RecruitingObservational study
All ages ยท All sexes ยท Updated Dec 18, 2025 ยท NCT04815005Lipoprotein Interactions and Platelet Function in Healthy Individuals and Those With Lipid Disorders
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 69 ยท All sexes ยท Updated Oct 1, 2025 ยท NCT06747000Alirocumab in Patients on a Stable Dialysis Regimen
RecruitingPhase 3
Ages 18 to 80 ยท All sexes ยท Updated Feb 12, 2020 ยท NCT03480568From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.