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Esophageal Adenocarcinoma clinical trials in Massachusetts

13 studies for Esophageal Adenocarcinoma are looking for participants at sites in Massachusetts.

Cities in Massachusetts

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

  • Dana-Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07544589

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

  • Boston Medical Center, Boston
  • Dana-Farber Cancer Institute, Boston
  • Dana-Farber Cancer Institute at Boston Medical Center - Brighton, Brighton
  • and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05677490

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

  • Brigham and Women's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
  • Dana-Farber Cancer Institute - Chestnut Hill, Newton
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07090499

Study of Denikitug (GS-1811) Given Alone or With Nivolumab or Chemotherapy in Adults With Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas

  • Massachusetts General Hospital, Boston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07546812

Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

  • Beth Israel Deaconess Medical Center, Boston
Recruiting
Ages 18 to 89 · All sexes · Updated Sep 11, 2026 · NCT05753748

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

  • Normunity Investigational Site, Boston
  • Normunity Investigational Site, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07182149

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

  • Massachusetts General Hospital, Boston
  • Brigham & Women's Hospital, Boston
  • Beth Israel Deaconess Medical Center,East Campus Research Pharmacy, Boston
  • and 3 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

  • Dana-Farber Cancer Institute, Boston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT07675967

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

  • Research Site, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07284186

Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

  • I-Mab Site 1002, Boston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT07432295

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

  • Mass General Hospital, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04900818

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.