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Melanoma clinical trials in Kentucky

21 studies for Melanoma are looking for participants at sites in Kentucky.

Cities in Kentucky

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • CommonSpirit Saint Joseph Hospital - Bardstown, Bardstown
  • Commonwealth Cancer Center-Corbin, Corbin
  • Saint Elizabeth Healthcare Edgewood, Edgewood
  • and 5 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of BI 3810944 in Patients With Advanced Cancer

  • University of Louisville, Louisville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07224425

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

  • Markey Cancer Center Clinical Research Organization, Lexington
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06246916

Pan-tumor MRD Study

  • Baptist Health Corbin, Corbin
  • Baptist Health Hardin, Elizabethtown
  • Baptist Health Lexington, Lexington
  • and 1 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma

  • CommonSpirit Saint Joseph Hospital - Bardstown, Bardstown
  • Commonwealth Cancer Center-Corbin, Corbin
  • CommonSpirit Saint Joseph Hospital - Lexington, Lexington
  • and 5 more
RecruitingPhase 3
Ages 75 and older · All sexes · Updated Sep 24, 2026 · NCT07068074

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

  • Mercy Health - Paducah Medical Oncology and Hematology, Paducah
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

  • University of Kentucky/Markey Cancer Center, Lexington
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT05896839

Project: Every Child for Younger Patients With Cancer

  • University of Kentucky/Markey Cancer Center, Lexington
  • Norton Children's Hospital, Louisville
RecruitingObservational study
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

  • Norton Cancer Institute, Louisville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

  • James Graham Brown Cancer Center (Melanoma/NSCLC), Louisville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT06060613

A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

  • University of Louisville, Louisville
RecruitingPhase 1/2
Ages 18 to 70 · All sexes · Updated Jun 11, 2026 · NCT05361174

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

  • University of Kentucky, Lexington
RecruitingPhase 1/2
Ages 18 to 90 · All sexes · Updated Jun 10, 2026 · NCT05655312

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

  • Flaget Memorial Hospital, Bardstown
  • Saint Joseph Hospital East, Lexington
  • Saint Joseph London, London
  • and 2 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

  • St Elizabeth Healthcare (St Elizabeth Medical Center), Edgewood
  • St Elizabeth Healthcare (St Elizabeth Medical, Edgewood
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT05549297

Nilotinib Plus Dabrafenib/Trametinib or Encorafenib/Binimetinib in Metastatic Melanoma

  • Markey Cancer Center, Lexington
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT04903119

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

  • Research Site 115, Louisville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

Beta Glucan's Effect on Pembrolizumab Immunologic Response in Stage III-IV Melanoma

  • University of Louisville, Louisville
Recruiting
Ages 18 and older · All sexes · Updated Oct 30, 2025 · NCT04513028

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

  • University of Kentucky, Lexington
Recruiting
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883

Neoadjuvant Combination Immunotherapy for Stage III Melanoma

  • University of Louisville, Louisville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 2, 2024 · NCT03842943

The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid Tumors

  • Baptist Health Clinical Research, Elizabethtown
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 27, 2022 · NCT05037825

A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients

  • James Graham Brown Cancer Center-University of Louisville, Louisville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 29, 2021 · NCT01638676

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.