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Small Cell Lung Cancer clinical trials in Texas

41 studies for Small Cell Lung Cancer are looking for participants at sites in Texas.

Cities in Texas

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

  • New Experimental Therapeutics - NEXT Oncology, Austin
  • Texas Oncology, Bedford
  • UT Southwest Simmons Cancer Center, Dallas
  • and 2 more
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

  • NEXT Dallas, Irving
  • NEXT Oncology, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT03460977

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

  • NEXT Oncology, Austin
  • UT Southwestern, Dallas
RecruitingPhase 1
Ages 19 and older · All sexes · Updated Oct 1, 2026 · NCT06586957

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07189871

Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer

  • Texas Oncology - Northeast Texas, Allen
  • Texas Oncology - DFW, Arlington
  • Texas Oncology - DFW, Arlington
  • and 33 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07226999

DESTINY-PANTUMOUR04

  • Research Site, Dallas
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

  • Baylor, Scott and White Research Institute, Dallas
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

  • The University of Texas MD Anderson Cancer Center /ID# 280070, Houston
  • Texas Oncology - Northeast Texas /ID# 280642, Tyler
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07365241

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

  • Next Oncology - Austin, Austin
  • Next Oncology - Houston, Houston
  • Next Oncology - Dallas, Irving
  • and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07488676

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

  • Oncology Consultants, P.A., Houston
  • University of Texas M.D. Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors

  • Site 1005, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07407933

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

  • Texas Oncology - Central South, Austin
  • University of Texas Southwestern Medical Center/Clinical Research Department, Dallas
  • Texas Oncology - West Texas, Odessa
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07218146

A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07564401

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

  • Avenzo Therapeutics Recruiting Site, Dallas
  • Avenzo Therapeutics Recruiting Site, Houston
  • Avenzo Therapeutics Recruiting Site, San Antonio
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

  • The University of Texas MD Anderson Cancer Center, Houston
  • Texas Oncology Cancer Center, Sugar Land
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT06712355

Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors

  • MD Anderson Cancer Center Uni of Te, Houston
RecruitingPhase 1/2
Ages 18 to 100 · All sexes · Updated Aug 27, 2026 · NCT06726148

A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

  • Texas Oncology - DFW, Dallas
  • MD Anderson Cancer Center, Houston
  • Texas Oncology - Northeast, Tyler
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06892548

A First-in-human (FIH), Phase 1 Study of ML261, an Autologous Potency Enhanced Anti-DLL3 CAR T Cell Therapy, in Participants With R/R SCLC or Select NECs (SPECTRAL-1)

  • UT Southwestern Medical Center, Dallas
  • MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07488923

A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer

  • Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas
  • University of Texas Southwestern Medical Center, Dallas
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06095505

A Study of MGC026 in Participants With Advanced Solid Tumors

  • The University of Texas MD Anderson Cancer Center, Houston
  • University of Texas Health Science Center at Houston, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

  • The University of Texas, MD Anderson Cancer Center, Houston
  • UT Health Mays Cancer Center, San Antonio
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

  • Houston Methodist Cancer Center, Houston
  • University of Texas Md Anderson Cancer Center, Houston
  • Texas Oncology, P.A. - Tyler, Tyler
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT06203210

A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

  • Clinical Trial Site, San Antonio
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07749586

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

  • The University of Texas MD Anderson Cancer Center, Houston
  • NEXT Dallas, Irving
  • South Texas Accelerated Research Therapeutics, LLC, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06131840

A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)

  • Mays Cancer Center / University of Texas, San Antonio, San Antonio
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT05652686

A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer

  • The University of Texas MD Anderson Cancer Center, Houston
  • Oncology Consultants, PA- Houston, Houston
  • Next Oncology Dallas, Irving
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT07174583

Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308)

  • University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT06598306

A Study of LY4175408 in Participants With Advanced Cancer

  • MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT07046923

Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors

  • START Dallas, Fort Worth
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT07517198

AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors

  • NEXT Oncology, Irving
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT07454642

Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors

  • NEXT Oncology Austin, Austin
  • NEXT Oncology San Antonio, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT07424547

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

  • M D Anderson Cancer Center, Houston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT06769126

Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

  • Michael E. DeBakey VA Medical Center, Houston, TX, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 11, 2026 · NCT06681220

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

  • NEXT Oncology - Dallas, Dallas
  • START San Antonio, San Antonio
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

  • Mary Crowley Cancer Research, Dallas
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT05490472

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

  • The University of Texas MD Anderson Cancer Center (site 127), Houston
RecruitingPhase 1/2
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

  • Research Site 135, Austin
  • Research Site 120, Dallas
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

  • The University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2025 · NCT06805825

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.