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Myelodysplastic Syndromes clinical trials in Florida

31 studies for Myelodysplastic Syndromes are looking for participants at sites in Florida.

Cities in Florida

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

  • UF Health Cancer Institute - Gainesville, Gainesville
  • Miami Cancer Institute, Miami
  • Memorial Hospital West, Pembroke Pines
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06577441

A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

  • Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 12 to 78 · All sexes · Updated Sep 29, 2026 · NCT03802695

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

  • UF Health Cancer Institute - Gainesville, Gainesville
  • Mayo Clinic in Florida, Jacksonville
  • Miami Cancer Institute, Miami
  • and 2 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05564390

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

  • Mayo Clinic Jacksonville, Jacksonville
  • Sylvester Cancer Center - U Miami, Miami
  • Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT05320198

A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

  • University of Miami, Miami
  • BRCR Medical Center Inc, Tamarac
  • Moffitt Cancer Center, Tampa
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07422480

A Study of BGB-11417 in Participants With Myeloid Malignancies

  • Tampa General Hospital, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04771130

A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia.

  • University of Miami, Miami
RecruitingPhase 2Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06566742

A Phase Ib Study of Rezatapopt in Combination With Azacitidine in Patients With TP53Y220C Mutant Myeloid Malignancies (Acute Myeloid Leukemia or Myelodysplastic Syndrome)

  • Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06616636

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

  • Broward Health Medical Center, Fort Lauderdale
  • Golisano Children's Hospital of Southwest Florida, Fort Myers
  • UF Health Cancer Institute - Gainesville, Gainesville
  • and 9 more
RecruitingPhase 1/2
Up to age 22 · All sexes · Updated Aug 25, 2026 · NCT04726241

A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

  • University of Miami Hospital and Clinics, Miami
  • Moffitt Cancer Center, Tampa
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06499285

A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS)

  • University of Miami School of Medicine Sylvester Comprehensive Cancer Center (SCCC), Miami
  • H. Lee Moffitt Cancer Center and Research Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT04419649

ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

  • H Lee Moffitt Cancer Center & Research Institute, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06656494

eHealth Mindfulness-based Music Therapy Intervention for Patients Undergoing Stem Cell Transplantation

  • University of Miami, Miami
Recruiting
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT07469592

Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)

  • University of Miami, Miami
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT05308264

Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

  • Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT07216443

Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

  • University of Florida, Gainesville
RecruitingPhase 2
6 Months – 39 Years · All sexes · Updated Jun 4, 2026 · NCT05800210

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

  • University of Miami - Sylvester Comprehensive Cancer Center, Miami
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT04256317

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

  • Mayo Clinic in Florida, Jacksonville
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT05969860

A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

  • Mayo Clinic Florida, Jacksonville
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT05732103

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

  • University of Miami, Miami
  • Miami Cancer Institute, Miami
  • Moffitt Cancer Center, Tampa
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)

  • Moffitt Cancer Center, Tampa
RecruitingPhase 2
Ages 1 to 60 · All sexes · Updated Mar 12, 2026 · NCT03970096

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

  • Sylvester Comprehensive Cancer Center, Miami
Recruiting
Ages 18 and older · All sexes · Updated Feb 20, 2026 · NCT05745285

CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

  • University of Miami Health System, Miami
  • Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT05143996

Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome

  • Mayo Clinic, Jacksonville
  • University of Miami, Miami
  • AdventHealth Medical Group & Bone Marrow Transplant at Orlando, Orlando
  • and 1 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Dec 23, 2025 · NCT04245397

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Jacksonville
  • Massive Bio SYNERGY-AI site, Miami
  • Massive Bio SYNERGY-AI site, Tampa
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

  • Sylvester Comprehensive Cancer Center, Miami
  • Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT06501196

Study of REM-422 in Patients With AML or Higher Risk MDS

  • Moffitt Cancer Center, Tampa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 23, 2025 · NCT06297941

The International PNH Interest Group PNH Registry

  • International PNH Interest Group, Altamonte Springs
RecruitingObservational study
All ages · All sexes · Updated Jul 29, 2024 · NCT06524726

Study in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Patients to Determine the Recommended Dose of CYAD-02

  • Mayo Clinic Cancer Center, Jacksonville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 9, 2020 · NCT04167696

A Study of LB-100 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)

  • H. Lee Moffitt Cancer Center & Research Institute, Tampa
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 8, 2019 · NCT03886662

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.