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Post-Traumatic Stress Disorder clinical trials recruiting in the U.S.

248 studies for Post-Traumatic Stress Disorder are recruiting participants at sites across the United States.

 You can get Post-Traumatic Stress Disorder (PTSD) after experiencing a traumatic event. PTSD starts at different times for different people.

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Recently updated studies

Induction of Dreaming With EEG and Anesthesia for Post-traumatic Stress Disorder

RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Oct 2, 2026 · NCT06577636

HBOT Effects on First Responders' Cognition and Well-Being

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 1, 2026 · NCT07852728

Psilocybin-Assisted Therapy

RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07332143

Hyperbaric Oxygen Therapy for Veterans With TBI and PCS: A Biomarker Study

RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 30, 2026 · NCT07849465

RISE Versus Advocacy-based Enhanced Care as Usual for Patients Experiencing IPV

Recruiting
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06906302

Treatment for PTSD and Tinnitus

Recruiting
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07106593

Integrated Health Care for PTSD

Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07220681

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1

RecruitingHealthy volunteers welcome
Ages 18 to 35 · All sexes · Updated Sep 23, 2026 · NCT04916327

An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07836647

NightWare and Cardiovascular Health in Veterans With PTSD

RecruitingHealthy volunteers welcome
Ages 22 to 88 · All sexes · Updated Sep 22, 2026 · NCT06419959

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07071350

Inflammatory Challenge and Fear

RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 21, 2026 · NCT06630884

Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study

RecruitingPhase 1
Ages 21 to 65 · All sexes · Updated Sep 21, 2026 · NCT06335407

Mobile Anger Reduction Intervention

Recruiting
All ages · All sexes · Updated Sep 21, 2026 · NCT06094933

Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSD

Recruiting
Ages 30 to 55 · All sexes · Updated Sep 21, 2026 · NCT05380050

Multifaceted Intervention to Restore Resilience and Overcome Risk

Recruiting
Ages 18 and older · Women · Updated Sep 21, 2026 · NCT06988787

Safety and Efficacy of Cannabidiol (CBD) for Symptoms of PTSD in Adults

RecruitingPhase 2
Ages 21 to 65 · All sexes · Updated Sep 17, 2026 · NCT05269459

An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)

RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07456696

Intensive Multi-Couple Therapy for PTSD Versus Relationship Education in Military Couples

Recruiting
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06047691

Cervical Plexus Hydrodissection With D5W Versus NS for Treatment-Resistant PTSD

RecruitingPhase 4
Ages 19 to 90 · All sexes · Updated Sep 16, 2026 · NCT07382596

Targeted Plasticity Therapy for PTSD

Recruiting
Ages 22 to 79 · All sexes · Updated Sep 16, 2026 · NCT06266364

Piloting Virtual Reality Environments to Treat PTSD in Healthcare Workers

RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04887116

Exercise and Emotional Learning in Posttraumatic Stress Disorder

Recruiting
Ages 18 to 64 · All sexes · Updated Sep 16, 2026 · NCT06127342

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.