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Post-Traumatic Stress Disorder clinical trials in California
37 studies for Post-Traumatic Stress Disorder are looking for participants at sites in California.
Cities in California
Integrated Health Care for PTSD
- VA San Diego Healthcare System, San Diego
Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07220681Inflammatory Challenge and Fear
- San Francisco VA Health Care System, San Francisco
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 21, 2026 · NCT06630884An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)
- Sun Valley Research, Imperial
- Kadima Neuropsychiatry, La Jolla
- CalNeuro Research Group, Los Angeles
- and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07456696A Hybrid 1 Effectiveness-Implementation Trial of Partner-Assisted Prolonged Exposure for PTSD
- San Diego VA Healthcare System, San Diego
Recruiting
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06990191Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans
- University of California Los Angeles, Los Angeles
RecruitingHealthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Aug 31, 2026 · NCT05120635Massed Prolonged Exposure for PTSD in Substance Use Treatment
- VA San Diego Healthcare System, San Diego
Recruiting
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06296186Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure
- VA San Diego, San Diego
Recruiting
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06296589MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder
- VA Greater Los Angeles Healthcare System, Westwood campus, Los Angeles
- West Los Angeles Veteran Affairs, Los Angeles
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05790239Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans
- VA San Diego Healthcare System, San Diego, CA, San Diego
Recruiting
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06162741Cognitive Control Training for Extinction in PTSD
- VA San Diego Healthcare System, San Diego, CA, San Diego
Recruiting
Ages 18 to 65 · All sexes · Updated Aug 7, 2026 · NCT06629064SMART Therapist Training: A Hybrid Factorial-SMART Design
- VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto
Recruiting
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07010770The Effects of Very Brief Exposure on PTSD in U.S. Combat Veterans
- Brain Imaging Lab, Los Angeles
RecruitingHealthy volunteers welcome
Ages 18 to 50 · All sexes · Updated Jul 29, 2026 · NCT06218381Treatments for Insomnia in Veterans With PTSD
- VA Greater Los Angeles Healthcare System, Sepulveda, CA, Sepulveda
Recruiting
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT05194930Improving Behavioral Health for Caregivers and Children After Pediatric Injury
- Children's Hospital Los Angeles, Los Angeles
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT06856057Suvorexant for Treatment of AUD and PTSD
- University of California - Los Angeles, Los Angeles
RecruitingPhase 2
Ages 21 to 65 · All sexes · Updated Jun 23, 2026 · NCT06679062Computational Assessment of GABA Receptor Modulation in PTSD
- VA San Diego Healthcare System, San Diego, CA, San Diego
RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Jun 16, 2026 · NCT06852469Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD
- VA San Diego Healthcare System, San Diego, CA, San Diego
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 4, 2026 · NCT06194851Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)
- Acacia Research Center, Sunnyvale
Recruiting
Ages 18 to 70 · All sexes · Updated Apr 27, 2026 · NCT07523685Mental Health in Veterans and Families After Group Therapies
- Soul Medicine Institute, Santa Rosa
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Apr 27, 2026 · NCT01327690Early Intervention for Postpartum PTSD: Comparing Written Exposure and Capnometry-Guided Breathing Therapy
- Stanford University, Palo Alto
Recruiting
Ages 18 and older · Women · Updated Apr 24, 2026 · NCT07342530Improving Cognitive Rehabilitation Outcomes
- VA San Diego Healthcare System, San Diego, CA, San Diego
Recruiting
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT07055633Auricular Acupuncture on Emotional Distress in Service Members and Veterans With PTSD
- David Grant USAF Medical Center, Fairfield
- Naval Medical Center San Diego, San Diego
Recruiting
Ages 18 to 65 · All sexes · Updated Apr 24, 2026 · NCT07021352Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder
- San Francisco VA Medical Center, San Francisco, CA, San Francisco
RecruitingHealthy volunteers welcome
Ages 18 to 75 · All sexes · Updated Apr 21, 2026 · NCT05780177Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder
- VA Greater Los Angeles Healthcare System, North Hills
RecruitingHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Apr 15, 2026 · NCT05516277Biomolecular Characteristics of Reminder-Focused Positive-Psychiatry
- UCLA, Los Angeles
Recruiting
Ages 11 to 15 · All sexes · Updated Mar 27, 2026 · NCT04529031Induction of Dreaming With EEG and Anesthesia for Post-traumatic Stress Disorder
- Stanford University, Stanford
RecruitingPhase 2
Ages 18 to 70 · All sexes · Updated Feb 24, 2026 · NCT06577636Personalized Brain Stimulation to Treat Chronic Concussive Symptoms
- UCLA, Westwood, Los Angeles
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Feb 24, 2026 · NCT06073886The BEAR Program for Women With Trauma Who Have Suicidal Thoughts
- Stanford University School of Medicine, Stanford
Recruiting
Ages 18 to 75 · Women · Updated Feb 20, 2026 · NCT07346638Enhancing Rehabilitation for Veterans With Serious Mental Illness
- VA San Diego Healthcare System, San Diego, CA, San Diego
Recruiting
Ages 18 to 83 · All sexes · Updated Jan 30, 2026 · NCT06586164Phase IIa Trial of a Selective Glucocorticoid Receptor Antagonist in the Treatment of Veterans With Posttraumatic Stress Disorder (PTSD) (Seven Study)
- San Francisco VA Medical Center, San Francisco, CA, San Francisco
RecruitingPhase 2
Ages 18 to 69 · All sexes · Updated Jan 29, 2026 · NCT04452500OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit
- VA San Diego Healthcare System, San Diego, CA, San Diego
Recruiting
Ages 18 and older · All sexes · Updated Nov 3, 2025 · NCT05156112Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)
- UC San Diego, San Diego
RecruitingPhase 2/3
Ages 21 to 55 · All sexes · Updated Oct 24, 2025 · NCT06273527MDMA-assisted Cognitive Processing Therapy Versus Cognitive Processing Therapy for Veterans With Severe Posttraumatic Stress Disorder
- VA Palo Alto Health Care System / Stanford University, Palo Alto
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 31, 2025 · NCT05837845Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress
- Stanford University, Palo Alto
RecruitingHealthy volunteers welcome
Ages 11 to 17 · All sexes · Updated Jul 18, 2025 · NCT05701111Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
- VA Long Beach Healthcare System, Long Beach, CA, Long Beach
- San Francisco VA Medical Center, San Francisco, CA, San Francisco
RecruitingPhase 4
Ages 18 to 75 · All sexes · Updated Jul 18, 2025 · NCT03642028A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations
- Stanford University, Palo Alto
- UCSF Alliance Health Project, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Apr 24, 2025 · NCT06367764Targeting the Default Mode Network: A TMS-fMRI Study
- VA Palo Alto, Palo Alto
Recruiting
Ages 18 to 55 · All sexes · Updated Apr 3, 2024 · NCT05646732From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.