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Rectal Cancer clinical trials in New York City, NY

17 studies for Rectal Cancer are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

RecruitingPhase 3
  • Memorial Sloan Kettering Cancer Center ( Site 0095), New York
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06997497

A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07227636

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Columbia University, New York
  • NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • NYU Langone Health Perlmutter Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04165772

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

Recruiting
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673

A Phase I-II Study to Test the Safety and Efficacy of PD1 (AB122) and Adenosine Receptor (AB928) Antagonists With Chemotherapy After Short-Course Radiation for Rectal Cancer.

RecruitingPhase 2
  • Weill Cornell Medical College, New York
  • Brooklyn Methodist Hospital - NewYork Presbyterian, New York
  • New York Presbyterian Hospital - Queens, New York
Ages 18 to 90 · All sexes · Updated Jul 29, 2026 · NCT05024097

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

RecruitingPhase 3
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT06205485

The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer

Recruiting
  • Weill Cornell Medical College, New York
  • New York Presbyterian Hospital - Queens, New York
Ages 18 to 90 · All sexes · Updated Jun 15, 2026 · NCT05943210

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • NYU Langone Medical Center, New York
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

A Study of Response to Standard Treatment Before Surgery in People With Rectal Cancer

Recruiting
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06637462

Brodalumab in the Treatment of Immune-Related Adverse Events

RecruitingPhase 1
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT06673329

A Study of Tucatinib and Trastuzumab in People With Rectal Cancer

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated May 12, 2026 · NCT05672524

Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation

RecruitingObservational study
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Mar 12, 2026 · NCT04668872

Gemcitabine, Cisplatin, Nab-paclitaxel (GAP) and Cemiplimab for Locally Advanced Biliary Tract Cancer (BTC)

RecruitingPhase 2
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT07433673

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, New York
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Rectal Cancer trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.