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Obsessive-Compulsive Disorder clinical trials recruiting in the U.S.

46 studies for Obsessive-Compulsive Disorder are recruiting participants at sites across the United States.

People with obsessive-compulsive disorder (OCD) suffer from frequent, upsetting thoughts called obsessions. Read about the treatments available.

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Recently updated studies

OCD LIFU Target Engagement

Recruiting
Ages 18 to 60 · All sexes · Updated Oct 1, 2026 · NCT07558148

Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder

Recruiting
Ages 22 to 75 · All sexes · Updated Oct 1, 2026 · NCT06660225

Aerobic Exercise and Obsessive-Compulsive Disorder Symptoms

Recruiting
Ages 18 to 64 · All sexes · Updated Sep 29, 2026 · NCT07103902

Acceptance and Commitment Therapy for Religious OCD

Recruiting
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06647589

Developing Brain, Impulsivity and Compulsivity

RecruitingObservational study
Ages 6 to 80 · All sexes · Updated Sep 25, 2026 · NCT04631042

Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD

RecruitingPhase 1/2Healthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 22, 2026 · NCT04131829

Treating Adolescent Obsessive Compulsive Disorder With Transcranial Magnetic Stimulation

Recruiting
Ages 13 to 17 · All sexes · Updated Sep 8, 2026 · NCT07065669

Physiological Brain Atlas Development

RecruitingObservational study
Ages 6 to 90 · All sexes · Updated Aug 26, 2026 · NCT00575081

TMS + Exposure Therapy for Pediatric OCD

Recruiting
Ages 12 to 21 · All sexes · Updated Aug 21, 2026 · NCT05931913

Anxiety Skills Study

Recruiting
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07774481

Pilot Study of RR-HNK in OCD

RecruitingPhase 1/2
Ages 18 to 65 · All sexes · Updated Aug 12, 2026 · NCT06575075

Neural Mechanisms of Response Inhibition Training for OCRD

Recruiting
Ages 18 to 60 · All sexes · Updated Aug 10, 2026 · NCT05377125

CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD

Recruiting
Ages 7 to 17 · All sexes · Updated Aug 4, 2026 · NCT05609916

Helping Adults With Obsessive-Compulsive Disorder Succeed at Work

Recruiting
Ages 18 to 60 · All sexes · Updated Jul 31, 2026 · NCT07124780

Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.

RecruitingMentions payment for participants
Ages 5 to 18 · All sexes · Updated Jul 31, 2026 · NCT06934525

SONATA LIFU for OCD

RecruitingPhase 2
Ages 22 to 80 · All sexes · Updated Jul 27, 2026 · NCT07728994

Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.

RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT07347405

Neurophysiological Investigation of the Approach-avoidance Axis in OCD: Applications to Neuromodulation

Recruiting
Ages 22 to 64 · All sexes · Updated Jul 23, 2026 · NCT06596447

Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder

RecruitingHealthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Jul 23, 2026 · NCT06834217

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Jul 16, 2026 · NCT06376734

Mechanisms of Exposure Therapy for OCD

Recruiting
Ages 18 to 65 · All sexes · Updated Jun 25, 2026 · NCT06173752

Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder

Recruiting
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT05160129

Neural Correlates of Psychiatric Disorders

RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT04725409

Project EMPOWER-OCD

RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT07158801

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.