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Neural Correlates of Psychiatric Disorders

Neural Correlates of Neuropsychiatric Functions

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Undergoing SEEG monitoring at Vanderbilt University Medical Center
* At least 18 years of age
* English speaking

Exclusion Criteria:

* Age \<18
* Not able to complete questionnaires (e.g., unable to comprehend instructions or follow directions)

About the study

This ClincialTrials.gov record originally corresponded to the protocol approved under IRB # 202370. The study was expanded to include stimulation and recordings approved under new IRB #211037. The participant data originally acquired from IRB# 202370 will be included in this new record:

This study seeks to better understand the neural activity underlying neuro cognitive disorders. Resting state local field potential recordings will be collected from medically refractory epilepsy patients implanted with depth electrodes for seizure localization, and metrics of neural activity will be correlated with psychiatric symptoms as measured from questionnaires. Subjects will also participate in neuro cognitive tasks while neural recordings are performed, and/or receive neural stimulation through implanted depth electrodes. A better understanding of disordered neural activity underlying neuropsychiatric disorders may additionally contribute to novel methods for diagnosing, treating, and preventing these diseases.

Sponsor: Vanderbilt University Medical Center · Participants: 100 · Started: Mar 31, 2021

Contact the study team

• Lucas Chang, BA · Phone: 615-421-3046
• Sarah Bick, MD · Phone: 615-343-9822

Official record on ClinicalTrials.gov — NCT04725409

Locations in the U.S.

Conditions

• Mental Disorders
• Memory
• Depression
• Anxiety
• Obsessive-Compulsive Disorder

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.