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Pancreatic Cancer clinical trials in Texas

78 studies for Pancreatic Cancer are looking for participants at sites in Texas.

Cities in Texas

Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies

  • Research Site, Houston
  • Research Site, San Antonio
RecruitingPhase 1/2
Ages 18 to 130 · All sexes · Updated Oct 5, 2026 · NCT05417594

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

  • Texas Oncology - West Texas, Abilene
  • Texas Oncology - Austin, Austin
  • Texas Oncology - San Antonio, San Antonio
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07562152

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

  • UT MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05372614

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

  • University of Texas MD Anderson Cancer Center, Houston
  • South Texas Accelerated Research Therapeutics (START), San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

  • The University of Texas MD Anderson Cancer Center - Texas Medical Center, Houston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06760819

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

  • The University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

  • The University of Texas MD Anderson Cancer Center - Conroe, Conroe
  • University of Texas MD Anderson Cancer Center, Houston
  • The University of Texas, MD Anderson Cancer Center - West Houston, Houston
  • and 3 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07090499

A Study of PHN-012 in Patients With Advanced Solid Tumors

  • PHN-012-001 Site, Houston
  • PHN-012-001 Site, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

  • University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07621718

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

  • START Dallas Fort Worth, Fort Worth
  • MD Anderson, Houston
  • NEXT Oncology Houston, Houston
  • and 1 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

DESTINY-PANTUMOUR04

  • Research Site, Dallas
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

  • University of Texas Southwestern Medical Center - Simmons Cancer Center, Dallas
  • University of Texas Southwestern Medical Center-William P. Clements Jr. University Hospital, Dallas
  • University of Texas Southwestern Medical Center-Zale Lipshy University Hospital, Dallas
  • and 3 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

  • Texas Oncology - DFW, Dallas
  • University of Texas, Southwestern Medical Center, Dallas
  • University of Texas MD Anderson Cancer Center, Houston
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07252232

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

  • Investigative Site US067, Dallas
  • Investigative Site US062, Denison
  • Investigative Site US011, Houston
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07522073

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

  • UT Southwestern Medical Center at Dallas, Dallas
  • Houston Methodist Office of Graduate - Houston Methodist Neal Cancer Center at Texas Medical Center, Houston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07409272

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

  • Baylor College of Medicine, Houston
  • The University of Texas MD Anderson Cancer Center, Houston
  • NEXT Oncology Dallas, Irving
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • MD Anderson, Houston
  • NEXT Dallas, Irving
  • NEXT Oncology San Antonio, San Antonio
  • and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

  • The University of Texas MD Anderson Cancer Center, Houston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06271291

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

  • The University of Texas MD Anderson Cancer Center - Texas Medical Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

  • NEXT - Dallas, Dallas
  • NEXT, San Antonio
  • START - San Antonio, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07349537

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

  • Local Institution - 0085, Houston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

CREO - Microwave Ablation Feasibility Study

  • Memorial Hermann-Texas Medical Center, Houston
Recruiting
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07817147

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

  • University of Texas Southwestern/Children's Medical Center, Dallas
  • M D Anderson Cancer Center, Houston
  • Texas Children's Hospital, Houston
  • and 1 more
RecruitingObservational study
Up to age 17 · All sexes · Updated Sep 11, 2026 · NCT06651580

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

  • UT MD Anderson, Houston
  • NEXT Oncology, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

  • UT Southwestern/Simmons Cancer Center-Dallas, Dallas
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
RecruitingObservational study
Ages 50 to 75 · All sexes · Updated Sep 4, 2026 · NCT04239573

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

  • The University of Texas - MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation

  • M D Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT03608631

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

  • START Dallas, Fort Worth
  • MD Anderson Cancer Center, Houston
  • START- San Antonio, San Antonio
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07644559

PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)

  • University of Texas Southwestern Medical Center, Dallas
  • The University of Texas MD Anderson Cancer Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06673017

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

  • Ut Southwestern, Dallas
  • Texas Oncology - DFW, Fort Worth
  • MDACC, Houston
  • and 2 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05245500

Alpha Radiation Emitters (DaRT) With Chemotherapy for the Treatment of Locally Advanced and Metastatic Pancreatic Cancer

  • Texas Oncology, Houston
  • Baylor College of Medicine, Houston
  • University Cancer and Diagnostic, Houston
Recruiting
Ages 18 to 120 · All sexes · Updated Aug 27, 2026 · NCT06698458

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

  • START San Antonio, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

Th-1 Dendritic Cell Immunotherapy Plus Standard Chemotherapy for Pancreatic Adenocarcinoma

  • Baylor College of Medicine Medical Center - McNair Campus, Houston
  • Baylor St. Lukes Medical Center, Houston
  • Dan L. Duncan Cancer Center at Baylor College of Medicine, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT04157127

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

  • Houston Methodist San Jacinto Hospital, Baytown
  • UT MD Anderson - The Woodlands, Conroe
  • Houston Methodist Cypress Hospital, Cypress
  • and 16 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06958328

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

  • MD Anderson Cancer Center, Houston
  • NEXT Dallas, Irving
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT07066657

A Study of MGC026 in Participants With Advanced Solid Tumors

  • The University of Texas MD Anderson Cancer Center, Houston
  • University of Texas Health Science Center at Houston, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470

A Study of DM002 in Patients With Advanced Solid Tumors

  • The University of Texas, MD Anderson Cancer Center, Houston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06751329

Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC)

  • Excel Diagnostics & Nuclear Oncology Center, Houston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT07733674

IDOV-Immune for Advanced Solid Tumors

  • MD Anderson Cancer Center, Houston
  • South Texas Accelerated Research Therapeutics, San Antonio
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06910657

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.