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High Blood Pressure clinical trials recruiting in the U.S.
186 studies for High Blood Pressure are recruiting participants at sites across the United States.
High blood pressure (hypertension) develops when blood flows through arteries at higher than normal pressures. It increases the risk for heart disease and stroke.
Cities with the most studies
- Chicago, IL22 studies
- Boston, MA21 studies
- Dallas, TX16 studies
- Nashville, TN13 studies
- Houston, TX11 studies
- Birmingham, AL11 studies
- Atlanta, GA10 studies
- Tucson, AZ10 studies
- Durham, NC10 studies
- New York City, NY9 studies
- Miami, FL9 studies
- Baltimore, MD9 studies
- Pittsburgh, PA8 studies
- Rochester, MN8 studies
- Arlington, VA8 studies
- Philadelphia, PA8 studies
- Cincinnati, OH8 studies
- Washington, DC8 studies
- Wichita, KS8 studies
- Cleveland, OH8 studies
- Charlotte, NC8 studies
- Winston-Salem, NC7 studies
- San Antonio, TX7 studies
- Richmond, VA7 studies
- Indianapolis, IN7 studies
- Salt Lake City, UT7 studies
- Detroit, MI7 studies
- Los Angeles, CA7 studies
- Orlando, FL7 studies
- Las Vegas, NV7 studies
- Mountain View, CA6 studies
- Austin, TX6 studies
- Harrisburg, PA6 studies
- New Orleans, LA6 studies
- Tampa, FL6 studies
- Knoxville, TN5 studies
- Kansas City, KS5 studies
- St. Louis, MO5 studies
- Kansas City, MO5 studies
- Columbia, SC5 studies
By state
- Alabama15 studies
- Arizona12 studies
- California28 studies
- Colorado12 studies
- Connecticut10 studies
- Florida21 studies
- Georgia20 studies
- Hawaii3 studies
- Idaho3 studies
- Illinois29 studies
- Indiana10 studies
- Iowa3 studies
- Kansas11 studies
- Kentucky5 studies
- Louisiana11 studies
- Maryland18 studies
- Massachusetts26 studies
- Michigan18 studies
- Minnesota16 studies
- Mississippi6 studies
- Missouri11 studies
- Nebraska5 studies
- Nevada9 studies
- New Jersey9 studies
- New Mexico3 studies
- New York14 studies
- North Carolina23 studies
- North Dakota3 studies
- Ohio18 studies
- Oklahoma9 studies
- Oregon3 studies
- Pennsylvania17 studies
- South Carolina14 studies
- Tennessee19 studies
- Texas27 studies
- Utah8 studies
- Virginia12 studies
- Washington4 studies
- West Virginia3 studies
- Wisconsin3 studies
Recently updated studies
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Oct 2, 2026 · NCT07142356Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
RecruitingObservational studyHealthy volunteers welcome
Ages 7 to 70 · All sexes · Updated Oct 2, 2026 · NCT03374215BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06059638Blood Pressure Lowering Strategies to Eliminate Hypertension Disparities (BLESSED)
Recruiting
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06133322A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
Recruiting
Ages 18 to 85 · All sexes · Updated Oct 1, 2026 · NCT07214376AM vs PM Exercise Training
Recruiting
Ages 55 to 80 · Women · Updated Oct 1, 2026 · NCT06042439A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07783802Improving Hypertension Control in Safety-Net Settings: The Boston Hypertension Equity Alliance in Treatment
Recruiting
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06948838EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07064473Autonomic and Renal Contributions to Hypertension With ADT
RecruitingPhase 4Healthy volunteers welcome
Ages 40 and older · Men · Updated Sep 30, 2026 · NCT07848828Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07511361Obstructive Sleep Apnea Among Somali-Americans
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT04124848Diabetes and Heart Disease Risk in Blacks
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Sep 28, 2026 · NCT00001853A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07794579A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06742723: Vascular Function in Health and Disease
RecruitingPhase 1Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT02966665Cardiovascular Effects of Angiotensin-(1-7) in Obesity Hypertension
RecruitingEarly phase 1
Ages 18 to 65 · All sexes · Updated Sep 24, 2026 · NCT06482853THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
Recruiting
Ages 22 to 75 · All sexes · Updated Sep 24, 2026 · NCT06559891Treatment With Aspirin After Preeclampsia: TAP Trial
RecruitingPhase 4
Ages 18 to 55 · Women · Updated Sep 22, 2026 · NCT06281665Lifestyle Intervention In CKD
Recruiting
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07633145Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109Improving the Collaborative Health of Adult Dyads
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05370014Study of Disrupted Sleep in Somali Americans
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 70 · All sexes · Updated Sep 14, 2026 · NCT05411029OBPM_PANDA2026: Evaluation of the Performance and Safety of the Aktiia Periodic Optical Blood Pressure Monitoring Device
RecruitingHealthy volunteers welcome
Ages 22 to 59 · All sexes · Updated Sep 14, 2026 · NCT07507903A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 14, 2026 · NCT07553442From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.