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Treatment-Resistant Depressive Disorder clinical trials in Ohio

5 studies for Treatment-Resistant Depressive Disorder are looking for participants at sites in Ohio.

Cities in Ohio

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

  • Neuro-Behavioral Clinical Research, North Canton
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 14, 2026 · NCT07284667

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

  • The Cleveland Clinic Foundation, Cleveland
  • The Ohio State University, Columbus
Recruiting
Ages 22 to 70 · All sexes · Updated Aug 28, 2026 · NCT06423430

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

  • The Ohio State University, Columbus
  • Charak Center for Health and Wellness, Garfield Heights
Recruiting
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03887715

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

  • The Ohio State University, Columbus
  • Neuro Behavioral Clinical Research, Inc., North Canton
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830

ALTO-207 in Adults With Treatment-resistant Depression (TRD)

  • Site 7029, Cincinnati
  • Site 7158, Garfield Heights
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Apr 28, 2026 · NCT07553637

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.