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Esophageal Cancer clinical trials in Nashville, TN

19 studies for Esophageal Cancer are looking for participants at sites in and around Nashville (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute, Nashville
  • Tennessee Oncology PLLC, Nashville
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute - Pharmacy, Nashville
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07090499

Phase 1 Study of PF-08046033 in Advanced Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute- Pharmacy, Nashville
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07519655

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Nashville
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

RecruitingPhase 1/2
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institue, Nashville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

RecruitingPhase 1
  • Sarah Cannon - Tennessee Oncology, Nashville
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute Oncology Partners (SCRI-Nashville), Nashville
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

RecruitingPhase 2
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06695845

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • US Oncology Research LLC, Nashville
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer Patients

RecruitingObservational study
  • Veterans Affairs Medical Center - Nashville, Nashville
  • Vanderbilt-Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT00899626

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Vanderbilt-Ingram Cancer Center, Nashville
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute (SCRI), Nashville
Ages 18 and older · All sexes · Updated Jan 12, 2026 · NCT07181473

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Nashville
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Esophageal Cancer

Early esophageal cancer does not have symptoms. Factors that increase risk include heavy drinking and smoking. Learn how you can reduce your risk.

More about Esophageal Cancer on MedlinePlus

Esophageal Cancer trials in other cities

Other studies in Nashville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.