🔎 Trials Near Me

Home › Prostate Cancer › Tennessee › Nashville

Prostate Cancer clinical trials in Nashville, TN

42 studies for Prostate Cancer are looking for participants at sites in and around Nashville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute, Nashville
  • Tennessee Oncology PLLC, Nashville
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Vanderbilt University/Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

RecruitingPhase 1
  • Tennessee Oncology, Nashville
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06095089

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Nashville
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
  • Urology Associates, Nashville
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06800313

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

RecruitingPhase 3
  • Tennessee Oncology, PLLC - Investigational Drug Services, Nashville
  • Tennessee Oncology, PLLC - Nashville Elliston Place Plaza Medical Oncology & Hematology Clinic, Nashville
  • Tennessee Oncology, PLLC - Nashville Saint Thomas West, Nashville
  • and 7 more
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07028853

A Study in Patients With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1
  • Tennessee Oncology, Nashville
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07719361

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 3
  • Sarah Cannon Research Institute Oncology Partners, Nashville
  • United States Oncology Regulatory Affairs Corporate Office, Nashville
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

RecruitingPhase 3
  • Research Site, Nashville
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06952803

A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer

RecruitingPhase 1/2
  • GSK Investigational Site, Nashville
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06990880

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

RecruitingPhase 2
  • Tennessee Valley Healthcare System Nashville Campus, Nashville, TN, Nashville
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT05011383

Phase 1 Trial to Study JANX013 and JANX007 Combination in mCRPC

RecruitingPhase 1
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT07813637

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

RecruitingPhase 3
  • SCRI Oncology Partners ( Site 0074), Nashville
  • Henry-Joyce Cancer Clinic ( Site 0042), Nashville
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 1
  • Sarah Cannon Research Institute Oncology Partners, Nashville
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07493512

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

RecruitingPhase 3
  • Urology Associates of Nashville, Nashville
Ages 18 and older · Men · Updated Sep 11, 2026 · NCT06056830

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Center, Nashville
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Activity of GDC-1261 in Participants With Advanced or Metastatic Prostate Cancer

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · Men · Updated Sep 4, 2026 · NCT07567846

Study of JANX014 in Subjects With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1
  • SCRI Oncology Partners, Nashville
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07545811

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

RecruitingPhase 2
  • Tennessee Oncology Nashville, Nashville
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07005154

AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)

RecruitingPhase 3
  • Research Site, Nashville
Ages 18 and older · Men · Updated Aug 26, 2026 · NCT07611110

Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

RecruitingPhase 2
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · Men · Updated Aug 24, 2026 · NCT07745361

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1
  • United States Oncology Regulatory Affairs Corporate Office, Nashville
Ages 18 and older · Men · Updated Aug 21, 2026 · NCT04221542

A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

RecruitingPhase 2
  • Henry-Joyce Cancer Clinic, Nashville
Ages 18 and older · Men · Updated Aug 17, 2026 · NCT06842498

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
  • Vanderbilt Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

RecruitingPhase 1
  • Sarah Cannon Research, Nashville
Ages 18 to 100 · Men · Updated Aug 13, 2026 · NCT05519449

Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

RecruitingPhase 1/2
  • Tennessee Oncology PLLC, Nashville
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07288359

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Investigative Site #102, Nashville
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06545942

PSMA PET Combined With MRI for the Detection of PCa

RecruitingPhase 3Healthy volunteers welcome
  • Urology Associates of Nashville, Nashville
Ages 18 and older · Men · Updated Jul 23, 2026 · NCT07052214

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

RecruitingPhase 3
  • Vanderbilt University/Ingram Cancer Center, Nashville
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • Sarah Cannon Research Institute (SCRI) Oncology Partners, Nashville
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

RecruitingPhase 1
  • Urology Associates PC, Nashville
Ages 18 and older · Men · Updated Feb 4, 2026 · NCT04729114

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Vanderbilt-Ingram Cancer Center, Nashville
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute (SCRI), Nashville
Ages 18 and older · All sexes · Updated Jan 12, 2026 · NCT07181473

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 136, Nashville
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Nashville
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

RecruitingPhase 3
  • Vanderbilt University/Ingram Cancer Center, Nashville
Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #6, Nashville
Ages 18 and older · All sexes · Updated Sep 5, 2025 · NCT05932862

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

RecruitingPhase 1/2
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated May 1, 2025 · NCT04503265

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Nashville

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.