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Gastrointestinal Cancers clinical trials in Massachusetts

15 studies for Gastrointestinal Cancers are looking for participants at sites in Massachusetts.

Cities in Massachusetts

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

  • Brigham and Women's Hospital (BWH), Boston
  • Dana-Farber Cancer Institute (DFCI), Boston
  • Dana-Farber Brigham Cancer Center - Foxborough, Foxborough
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

  • GSK Investigational Site, Boston
  • GSK Investigational Site, Boston
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07218926

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

  • Dana Farber Cancer Institute, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

SURGE: Supporting Utility and Representation in Genomics-based Cancer Trial Enrollment (Intervention)

  • Dana Farber Cancer Institute, Boston
  • Dana-Farber Cancer Institute at St. Elizabeth's Medical Center, Brighton
  • Dana-Farber Cancer Instiute - Merrimack Valley, Methuen
Recruiting
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05375643

Resilience and Equity in Aging, Cancer, and Health (REACH)

  • Dana-Farber Cancer Institute, Boston
Recruiting
Ages 65 and older · All sexes · Updated Sep 10, 2026 · NCT04674267

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

  • Brigham and Women's Hospital, Boston
  • Dana Farber Cancer Institute, Boston
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT04899908

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

  • Dana-Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07544589

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

  • Massachusetts General Hospital Cancer Center, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

BOLSTER: Learning New Skills to Thrive

  • Dana-Farber Cancer Institute, Boston
Recruiting
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT06936878

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

  • Massachusetts General Hospital,, Boston
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

  • Dana Farber Cancer Institute, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

  • Massachusetts General Hospital, Boston
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.