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Glioma clinical trials in New York City, NY

25 studies for Glioma are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Research Site, New York
  • Research Site, New York
Ages 18 to 130 · All sexes · Updated Oct 5, 2026 · NCT05417594

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

RecruitingPhase 1/2
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
12 Months – 21 Years · All sexes · Updated Oct 1, 2026 · NCT05099003

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

RecruitingPhase 2
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566

A Study of Mirdametinib in People With Central Nervous System Tumors

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07539441

Glioma Developmental and HyperActive Ras Tumor (DHART) Board

RecruitingObservational study
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT05489783

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

RecruitingPhase 3
  • NYU Langone Health, New York
  • Icahn School of Medicine at Mount Sinai, New York
  • Columbia University Medical Center, New York
  • and 1 more
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05303519

Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

RecruitingPhase 1
  • New York University, New York
Ages 1 to 25 · All sexes · Updated Aug 18, 2026 · NCT04485559

Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

RecruitingPhase 4
  • New York Presbyterian Hospital-Columbia University Medical Center, New York
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT07486713

A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma

RecruitingPhase 1
  • NYU Langone Health, New York
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07464925

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • Columbia University Irving Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

Pembrolizumab, Olaparib, and Temozolomide for People With Glioma

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05188508

Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Glioblastoma

Recruiting
  • NYU Langone Health, New York
Ages 18 to 85 · All sexes · Updated Jul 21, 2026 · NCT06910306

MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 1 to 26 · All sexes · Updated Jul 10, 2026 · NCT06712875

Chronic CED of TPT for Recurrent Malignant Glioma

RecruitingPhase 1
  • Columbia University Irving Medical Center / NewYork-Presbyterian Hospital, New York
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT06666712

A Study of 177Lu-PSMA-617 in People With Gliomas

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT07223034

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

RecruitingPhase 3
  • Lenox Hill Brain Tumor Center, New York
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT05271240

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

Recruiting
  • Lenox Hill Brain Tumor Center, New York
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT05954858

Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)

Recruiting
  • Lenox Hill Brain Tumor Center, New York
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT05979064

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

RecruitingPhase 1
  • Laura & Isaac Perlmutter Cancer Center at NYU Langone Health, New York
  • Columbia University Medical Center, New York
  • Memorial Slone Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT06326411

Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252

RecruitingPhase 1
  • Memorial Sloan Kettering, New York
Ages 18 and older · All sexes · Updated Apr 15, 2026 · NCT06126744

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

RecruitingPhase 1/2
  • NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA

RecruitingPhase 2
  • Lenox Hill Brain Tumor Center, New York
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT02800486

FUS Etoposide for DMG

RecruitingPhase 1
  • Columbia University Irving Medical Center, New York
Ages 4 to 21 · All sexes · Updated Jan 28, 2026 · NCT05762419

Concurrent XRD-0394 With Radiation Therapy for High Grade Gliomas

RecruitingEarly phase 1
  • NYU Langone Health, New York
Ages 18 and older · All sexes · Updated Jan 2, 2026 · NCT06829173

Glioma trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.