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Glioma clinical trials in Seattle, WA

11 studies for Glioma are looking for participants at sites in and around Seattle (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

RecruitingPhase 1/2
  • Seattle Children's Hospital, Seattle
12 Months – 21 Years · All sexes · Updated Sep 25, 2026 · NCT05099003

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

RecruitingPhase 2
  • Seattle Children's Hospital, Seattle
12 Months – 39 Years · All sexes · Updated Sep 21, 2026 · NCT06838676

Targeted Pediatric High-Grade Glioma Therapy

RecruitingObservational study
  • Seattle Children's Hospital, Seattle
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379

Study of Olutasidenib and Temozolomide in HGG

RecruitingPhase 2
  • Seattle Children's Hospital, Seattle
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

RecruitingPhase 3
  • Fred Hutch Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05303519

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

RecruitingPhase 2
  • Seattle Children's Hospital, Seattle
Ages 3 to 39 · All sexes · Updated Aug 24, 2026 · NCT05096481

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • University of Washington School of Medicine, Seattle
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

RecruitingEarly phase 1Healthy volunteers welcome
  • Seattle Children's Hospital, Seattle
Ages 1 to 21 · All sexes · Updated Jun 29, 2026 · NCT06333899

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

RecruitingPhase 2
  • Seattle Children's Hospital, Seattle
12 Months – 39 Years · All sexes · Updated May 29, 2026 · NCT05843253

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

RecruitingEarly phase 1
  • Seattle Children's Hospital, Seattle
Up to age 21 · All sexes · Updated Mar 18, 2026 · NCT04655404

Glioma trials in other cities

Other studies in Seattle

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.