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Kidney Cancer (Renal Cell Carcinoma) clinical trials in Pennsylvania
26 studies for Kidney Cancer (Renal Cell Carcinoma) are looking for participants at sites in Pennsylvania.
Cities in Pennsylvania
- Pittsburgh15 studies
- Philadelphia15 studies
- Harrisburg4 studies
- Erie4 studies
- Allentown4 studies
- Hazleton4 studies
- Scranton3 studies
A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors
- Research Site, Pittsburgh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05536141A Phase 1 Study of the Safety and Tolerability of CTX-10726
- UPMC Hillman Cancer Center, Pittsburgh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07419841Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)
- UPMC Cancer Center/Hillman Cancer Center ( Site 5017), Pittsburgh
RecruitingPhase 1/2
Ages 18 to 120 · All sexes · Updated Oct 2, 2026 · NCT07049926Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- Lehigh Valley Hospital-Cedar Crest, Allentown
- Lehigh Valley Hospital - Muhlenberg, Bethlehem
- Geisinger Medical Center, Danville
- and 7 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
- Exelixis Clinical Site #104, Hershey
- Exelixis Clinical Site #98, Philadelphia
- Exelixis Clinical Site #32, Pittsburgh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
- Lehigh Valley Hospital-Cedar Crest, Allentown
- Lehigh Valley Hospital - Muhlenberg, Bethlehem
- Pocono Medical Center, East Stroudsburg
- and 8 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382DESTINY-PANTUMOUR04
- Research Site, Philadelphia
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
- Lehigh Valley Hospital-Cedar Crest, Allentown
- UPMC-Heritage Valley Health System Beaver, Beaver
- Lehigh Valley Hospital - Muhlenberg, Bethlehem
- and 36 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05327686ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
- University of Pennsylvania, Philadelphia
- WellSpan Medical Oncology & Hematology at York Cancer Center, York
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC)
- Penn State Cancer Institute, Hershey
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07188896Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
- Lehigh Valley Hospital-Cedar Crest, Allentown
- UPMC-Heritage Valley Health System Beaver, Beaver
- Lehigh Valley Hospital - Muhlenberg, Bethlehem
- and 23 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06661720A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors
- Research Site, Pittsburgh
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07115043Study of DCC-2812 in Participants With Advanced Genitourinary Cancers
- Fox Chase Cancer Center, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06966024Neoadjuvant Pembrolizumab and Lenvatinib for Renal Cell Carcinoma
- Abramson Cancer Center at University of Pennsylvania, Philadelphia
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT05733715A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)
- Fox Chase Cancer Center, Philadelphia
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT07195682Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors
- Fox Chase Cancer Center, Philadelphia
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT05263050A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors
- Thomas Jefferson University Hospital, Philadelphia
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT03972657Autologous Dendritic Cell Vaccine in Kidney Cancer
- UPMC Department of Urology, Pittsburgh
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05127824KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
- UPMC Hillman Cancer Center, Pittsburgh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT06026410Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors
- Perelman Center for Advanced Medicine /ID# 250188, Philadelphia
- UPMC Hillman Cancer Ctr /ID# 225706, Pittsburgh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT04777994A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body
- University of Pittsburgh Medical Center - Hillman Cancer Center, Pittsburgh
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 28, 2026 · NCT06413680Patient Preference for Subcutaneous vs. Intravenous Immune Therapy
- UPMC Hillman Cancer Center, Pittsburgh
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT07223424Pencil Beam Scanning in Patients With Renal Tumors
- Children's Hospital of Philadelphia, Philadelphia
RecruitingEarly phase 1
Ages 0 to 30 · All sexes · Updated Apr 15, 2026 · NCT03810651A Study of VET3-TGI in Patients With Solid Tumors
- UPMC- Hillman Cancer Center, Pittsburgh
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT06444815Contrast-Enhanced Ultrasound Imaging for Diagnosing Recurrent Renal Cell Carcinoma (RCC) Post Ablation
- Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT05641935Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
- UPMC Altoona, Altoona
- UPMC-Heritage Valley Health System Beaver, Beaver
- UPMC Hillman Cancer Center at Butler Health System, Butler
- and 20 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT04510597From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.