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Kidney Cancer (Renal Cell Carcinoma) clinical trials in Philadelphia, PA

15 studies for Kidney Cancer (Renal Cell Carcinoma) are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Reading Hospital McGlinn Cancer Institute at Phoenixville, Phoenixville · 22 mi away
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #98, Philadelphia
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Philadelphia
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

RecruitingPhase 2
  • Christiana Care Health System-Concord Health Center, Chadds Ford · 23 mi away
  • Christiana Care Health System-Wilmington Hospital, Wilmington · 25 mi away
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05327686

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

RecruitingPhase 3
  • Thomas Jefferson University Hospital, Philadelphia
  • Jefferson Torresdale Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06661720

Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

RecruitingPhase 1
  • Fox Chase Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06966024

Neoadjuvant Pembrolizumab and Lenvatinib for Renal Cell Carcinoma

RecruitingEarly phase 1Healthy volunteers welcome
  • Abramson Cancer Center at University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT05733715

A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

RecruitingPhase 1
  • Fox Chase Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT07195682

Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors

RecruitingPhase 2
  • Fox Chase Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT05263050

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

RecruitingPhase 1
  • Perelman Center for Advanced Medicine /ID# 250188, Philadelphia
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT04777994

Pencil Beam Scanning in Patients With Renal Tumors

RecruitingEarly phase 1
  • Children's Hospital of Philadelphia, Philadelphia
Ages 0 to 30 · All sexes · Updated Apr 15, 2026 · NCT03810651

Contrast-Enhanced Ultrasound Imaging for Diagnosing Recurrent Renal Cell Carcinoma (RCC) Post Ablation

RecruitingPhase 2
  • Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT05641935

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

RecruitingPhase 3
  • UPMC Hillman Cancer Center - Part of Frick Hospital, Mount Pleasant · 8 mi away
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT04510597

Kidney Cancer (Renal Cell Carcinoma) trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.