🔎 Trials Near Me

Home › Lung Cancer › Tennessee › Nashville

Lung Cancer clinical trials in Nashville, TN

40 studies for Lung Cancer are looking for participants at sites in and around Nashville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

RecruitingPhase 3
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06765109

A Study of PHN-012 in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • PHN-012-001 Site, Nashville
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

RecruitingPhase 3
  • SCRI Oncology Partners - Tennessee, Nashville
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06881784

Phase 1 Study of PF-08046033 in Advanced Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute- Pharmacy, Nashville
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07519655

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

RecruitingPhase 3
  • Sarah Cannon Research Institute, Nashville
  • United States Oncology Regulatory Affairs Corporate Office, Nashville
Ages 18 to 100 · All sexes · Updated Sep 25, 2026 · NCT05920356

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

RecruitingPhase 3
  • SCRI Oncology Partners, Nashville
  • Tennessee Oncology, PLLC-Elliston Place Plaza Medical Oncology &Hematology, Nashville
  • Tennessee Oncology, PLLC - Saint Thomas West, Nashville
  • and 3 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

RecruitingPhase 2
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07154290

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

RecruitingPhase 2
  • Research Site, Nashville
  • Research Site, Nashville
Ages 18 to 95 · All sexes · Updated Sep 23, 2026 · NCT05061550

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

RecruitingPhase 2/3
  • Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06712316

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

RecruitingPhase 2/3
  • Tennessee Oncology, Nashville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07100080

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institue, Nashville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • Tennessee Oncology, PLLC, Nashville
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • Sarah Canon Research Institute (SCRI) Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute, Nashville
  • SCRI Oncology Partners, Nashville
  • Vanderbilt-Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Tennessee Oncology, Nashville
  • USO - US Oncology Research Network, Nashville
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

RecruitingPhase 1
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06343402

Collecting and Analyzing Tissue Samples From Patients Undergoing Surgery for Non-Small Cell Lung Cancer

RecruitingObservational study
  • Vanderbilt-Ingram Cancer Center, Nashville
Ages 18 to 120 · All sexes · Updated Aug 20, 2026 · NCT00897117

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute Oncology Partners (SCRI-Nashville), Nashville
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • Xencor Investigative Site, Nashville
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

RecruitingPhase 1/2
  • Tennessee Oncology, Nashville
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT06162221

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

RecruitingPhase 1
  • Sarah Cannon, SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT04678648

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

RecruitingPhase 1
  • Research Site, Nashville
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Molecular Predictors of Cancer in Patients at High Risk of Lung Cancer

RecruitingObservational study
  • Vanderbilt-Ingram Cancer Center, Nashville
  • Veterans Affairs Medical Center - Nashville, Nashville
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT00898313

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

RecruitingPhase 1/2
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Mar 20, 2026 · NCT05948865

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • Sarah Cannon Research Institute (SCRI) Oncology Partners, Nashville
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

EBUS-TBNA vs Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing

RecruitingPhase 4
  • Vanderbilt University/Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Feb 2, 2026 · NCT06105801

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Vanderbilt-Ingram Cancer Center, Nashville
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of TJ101 in Patients With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute (SCRI), Nashville
Ages 18 and older · All sexes · Updated Jan 12, 2026 · NCT07181473

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Nashville
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

RecruitingPhase 1/2
  • Tennessee Oncology, Nashville
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT05941507

Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer

RecruitingPhase 1/2
  • Vanderbilt University/Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Oct 17, 2024 · NCT05501665

Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation

RecruitingPhase 1/2
  • Vanderbilt University/Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Jun 20, 2024 · NCT06110572

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Nashville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.