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Mild Cognitive Impairment clinical trials in New York City, NY

24 studies for Mild Cognitive Impairment are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Deep Sleep in Older Adults

RecruitingPhase 2
  • SleepSpace, New York
  • SleepSpace, New York
Ages 55 and older · All sexes · Updated Oct 2, 2026 · NCT07316153

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

RecruitingPhase 3
  • Weill Cornell Medical College, New York
  • Adams Clinical Harlem, New York
Ages 50 to 90 · All sexes · Updated Sep 21, 2026 · NCT07177352

Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

RecruitingObservational study
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04916210

Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity

Recruiting
  • Columbia University, New York
Ages 55 and older · All sexes · Updated Sep 8, 2026 · NCT05655325

Olfactory Training in Mild Cognitive Impairment

Recruiting
  • New York State Psychiatric Institute, New York
Ages 55 to 89 · All sexes · Updated Sep 4, 2026 · NCT06825403

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • VA New York Harbor Healthcare System, New York
  • Weill Cornell Medical College, New York
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

RecruitingPhase 3
  • NYU Langone Health, New York
Ages 60 to 85 · All sexes · Updated Aug 20, 2026 · NCT06976216

Early Age-Related Hearing Loss Investigation (EARHLI)

Recruiting
  • Columbia University Medical Center, New York
Ages 55 to 75 · All sexes · Updated Aug 12, 2026 · NCT06174038

Improving Self-Care of Caregivers of Adults in Homecare With Heart Failure and Cognitive Impairment

Recruiting
  • VNS Health, New York
Ages 18 to 101 · All sexes · Updated Aug 12, 2026 · NCT07220798

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

Recruiting
  • New York University, New York
  • Mount Sinai, New York
Ages 55 to 85 · All sexes · Updated Aug 6, 2026 · NCT05988385

Autoimmune Features of Neurodegenerative Disorders

RecruitingObservational studyHealthy volunteers welcome
  • Columbia University Medical Center, New York
Ages 55 to 90 · All sexes · Updated Aug 4, 2026 · NCT04239079

Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease

Recruiting
  • Radial Midtown Manhattan, New York
Ages 22 to 80 · All sexes · Updated Jul 31, 2026 · NCT07207122

Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

RecruitingPhase 2
  • Columbia University Irving Medical Center, New York
Ages 55 to 89 · All sexes · Updated Jul 28, 2026 · NCT06601933

Digital Tools to Support Healthcare Decision Making

RecruitingHealthy volunteers welcome
  • Weill Cornell Medicine, New York
Ages 60 and older · All sexes · Updated Jul 8, 2026 · NCT07485725

Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease

RecruitingPhase 2Healthy volunteers welcome
  • Columbia University Irving Medical Center, New York
Ages 50 and older · All sexes · Updated Jul 6, 2026 · NCT04576793

Phase 2 - Rhythmic Light Therapy for Alzheimer's Disease Patients

Recruiting
  • Icahn School of Medicine at Mount Sinai, New York
Ages 55 and older · All sexes · Updated May 29, 2026 · NCT05016219

Safety Assessment of Leronlimab and Its Effect on Brain Inflammation in Alzheimer's Disease

RecruitingPhase 2
  • Weill Cornell Medicine Brain Health Imaging Institute, New York
Ages 50 and older · All sexes · Updated May 22, 2026 · NCT07553338

Genetic Studies of Early-onset Dementia

RecruitingObservational studyHealthy volunteers welcome
  • Columbia University Irving Medical Center, New York
Ages 35 and older · All sexes · Updated Apr 29, 2026 · NCT04906863

Evaluating the Efficacy of the Pain Identification and Communication Toolkit

Recruiting
  • Weill Cornell Medicine, New York
Ages 21 and older · All sexes · Updated Feb 12, 2026 · NCT06168604

Tau PET in Imaging and Cognition: Healthy Adults From 55-90

RecruitingObservational studyHealthy volunteers welcome
  • Columbia University Medical Center, New York
Ages 55 to 90 · All sexes · Updated Feb 11, 2026 · NCT03372317

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

RecruitingObservational studyHealthy volunteers welcome
  • Columbia University, New York
Ages 18 and older · All sexes · Updated Jan 15, 2026 · NCT05677880

Innate Immunity Stimulation Via TLR9 in Early AD

RecruitingPhase 1
  • NYU Langone Health, New York
Ages 60 to 85 · All sexes · Updated Jan 7, 2026 · NCT05606341

Study of ALTO-101 in Patients With Schizophrenia

RecruitingPhase 2
  • Site 5108, New York
  • Site 5077, New York
Ages 21 to 55 · All sexes · Updated Dec 26, 2025 · NCT06502964

Memory Support System for Older Chinese Americans With Mild Cognitive Impairment

Recruiting
  • Li Lab, Icahn School of Medicine at Mount Sinai, New York
Ages 55 and older · All sexes · Updated Nov 6, 2025 · NCT07142499

About Mild Cognitive Impairment

In mild cognitive impairment (MCI), you have more memory and thinking problems than others your age, but they don't interfere with your everyday life.

More about Mild Cognitive Impairment on MedlinePlus

Mild Cognitive Impairment trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.