Home › Alzheimer's Disease › NCT07177352
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
RecruitingPhase 3
Master Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies as Assessed by Biomarker Status and Cognition
Who can join
Ages 50 to 90 · All sexes
Full eligibility criteria
Inclusion Criteria:
* Ability and willingness to participate in an interventional clinical study, including meeting key eligibility criteria of linked interventional Roche AD studies (e.g., specific age ranges)
* Ability and willingness to receive information about potential eligibility in an associated interventional Roche AD study
Exclusion Criteria:
* Dependency in basic activities of daily living (bADLs) due to cognitive impairment
* Visual or auditory impairment that would prevent them from performing the cognitive assessments (eyeglasses and hearing aids are permitted)
* Any self-reported evidence or known diagnosis of a neurological or neurodegenerative condition that may lead to cognitive impairment other than AD
* History of severe, clinically significant central nervous system trauma
* Any serious medical condition that precludes a participant's safe participation and completion of a clinical study
* For participants with a clinical diagnosis of MCI or mild AD: Previous AD diagnosis based on biomarker confirmation with an approved or validated rule in method (e.g., amyloid PET or cerebrospinal fluid, blood biomarker) is exclusionary
About the study
This study is a pre-screening process used to assess participants' potential eligibility for Roche interventional Alzheimer's disease studies.
What is being tested
Sponsor: Hoffmann-La Roche · Participants: 80,000 · Started: Jul 2, 2025
Contact the study team
Official record on ClinicalTrials.gov — NCT07177352
Locations in the U.S.
| Alabama | University of Alabama at Birmingham, Birmingham |
| Arizona | Banner Alzheimer?s Institute, Phoenix Banner Sun Health Research Institute, Sun City |
| California | Sun Valley Research Center, Inc., Imperial Irvine Center for Clinical Research, Irvine Healthy Brain Clinic, Long Beach Inglewood Clinicals, Los Angeles Oakland Clinical, Oakland Riverside Clinical, Riverside Syrentis Clinical Research, Santa Ana Cenexel California Neuroscience Research, LLC, Sherman Oaks |
| Connecticut | Yale University, New Haven |
| Florida | JEM Research LLC, Atlantis K2 Medical Research-Winter Garden, Clermont K2 Medical Research - The Villages, Lady Lake K2 Medical Research, LLC, Maitland Visionary Investigators Network- Neurology Aventura, Miami Renstar Medical Research, Ocala Charter Research - Winter Park/Orlando, Orlando Conquest Research - Lake Nona, Orlando Alzheimer's Research and Treatment Center, Stuart Axiom Brain Health LLC, Tampa Charter Research - Lady Lake/The Villages, The Villages Alzheimer?s Research and Treatment Center, Wellington Conquest Research, LLC, Winter Park |
| Georgia | Grady Memorial Hospital, Atlanta Alzheimer's Research and Treatment Center - Columbus, Columbus Accel Research Sites-NeuroStudies, Decatur CenExel iResearch, LLC, Decatur Center for Advanced Research & Education, Gainesville |
| Hawaii | Hawaii Pacific Neuroscience, Honolulu |
| Illinois | Great Lakes Clinical Trials Chicago d/b/a Flourish Research Andersonville, Chicago RE:Cognition (Chicago), Chicago |
| Louisiana | Tandem Clinical Research, LLC, Marrero |
| Massachusetts | Adams Clinical Boston, Boston Boston Center for Memory, Newton Adams Clinical Watertown, Watertown |
| Michigan | Quest Research Institute, Farmington Hills |
| Missouri | Washington University School of MedicineClinical Translational Research Unit, St Louis |
| New Jersey | The Cognitive and Research Center of New Jersey, Ridgewood The Cognitive and Research Center of New Jersey, Springfield |
| New Mexico | IMA Clinical Research - Albuquerque, Albuquerque |
| New York | Basil Clinical, Laurelton Adams Clinical Harlem, New York Weill Cornell Medical College, New York AD-CARE, University of Rochester Medical Center, Rochester Adams Clinical Bronx, The Bronx |
| North Carolina | Triad Clinical Trials, Greensboro |
| Ohio | Ohio State University, Columbus |
| Oregon | Summit Research Network Inc., Portland |
| Pennsylvania | Flourish Research ? Philadelphia, Plymouth Meeting |
| Rhode Island | Butler Hospital, Providence |
| South Carolina | Ralph H. Johnson VA Medical Center, Charleston Palmetto Clinical Trials, Summerville |
| Tennessee | Genesis Neuroscience Clinic, Knoxville K2 Medical Research - Nashville, Nashville |
| Texas | Gadolin Research, LLC, Beaumont South Texas Research Institute - Brownsville, Brownsville Kerwin Medical Center, Dallas Kerwin Research Center, LLC, Dallas South Texas Research Institute - Edinburg, Edinburg Re:Cognition Health - Fort Worth, Fort Worth Re:Cognition Health - Houston, Houston Mt.Olympus Medical Research, Katy El Faro Health and Therapeutics, Rio Grande City |
| Virginia | Sana Research, LLC, Arlington Re:Cognition Health, Fairfax |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.