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Down Syndrome clinical trials in California
10 studies for Down Syndrome are looking for participants at sites in California.
Cities in California
Down Syndrome Obstructive Sleep Apnea
- Children's Hospital of Los Angeles, Los Angeles
RecruitingPhase 2
Ages 5 to 18 · All sexes · Updated Sep 30, 2026 · NCT06043440Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy
- Cedars-Sinai Medical Center, Los Angeles
- Sharp-Rees Stealy Medical Group, San Diego
- UCSD, San Diego
- and 2 more
RecruitingObservational study
Ages 18 and older · Women · Updated Sep 9, 2026 · NCT01429389Endotype DIrected Treatment for OSA in Down Syndrome
- University of California San Diego, San Diego
RecruitingPhase 4
Ages 6 and older · All sexes · Updated Sep 3, 2026 · NCT07280468A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
- Kaiser Permanente-Anaheim, Anaheim
- Kaiser Permanente Downey Medical Center, Downey
- Kaiser Permanente-Fontana, Fontana
- and 14 more
RecruitingPhase 2
Ages 1 to 30 · All sexes · Updated Sep 1, 2026 · NCT04546399A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
- Valley Children's Hospital, Madera
- UCSF Benioff Children's Hospital Oakland, Oakland
- Kaiser Permanente-Oakland, Oakland
- and 3 more
RecruitingObservational study
Ages 6 to 39 · All sexes · Updated Aug 25, 2026 · NCT05702645Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
- Lucile Packard Children's Hospital, Palo Alto
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment
- San Gabriel Valley Perinatal Medical Group, West Covina
RecruitingObservational study
All ages · Women · Updated Jun 12, 2026 · NCT07643896Collaboration for Down Syndrome Progress (CDP)
- University of California Irvine, Orange
RecruitingObservational study
All ages · All sexes · Updated Jun 4, 2026 · NCT07625579Trial-Ready Cohort-Down Syndrome (TRC-DS)
- University of California, Irvine School of Medicine, Co-Enrolling through ABC-DS Only, Orange
RecruitingObservational study
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109Pediatric Down Syndrome Post-Approval Study
- Children's Hospital Orange County, Orange
Recruiting
Ages 13 to 18 · All sexes · Updated Feb 28, 2025 · NCT06851338From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.