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Down Syndrome clinical trials in Orange, CA

4 studies for Down Syndrome are looking for participants at sites in and around Orange (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

RecruitingPhase 2
  • Children's Hospital of Orange County, Orange
Ages 1 to 30 · All sexes · Updated Sep 1, 2026 · NCT04546399

Collaboration for Down Syndrome Progress (CDP)

RecruitingObservational study
  • University of California Irvine, Orange
All ages · All sexes · Updated Jun 4, 2026 · NCT07625579

Trial-Ready Cohort-Down Syndrome (TRC-DS)

RecruitingObservational study
  • University of California, Irvine School of Medicine, Co-Enrolling through ABC-DS Only, Orange
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109

Pediatric Down Syndrome Post-Approval Study

Recruiting
  • Children's Hospital Orange County, Orange
Ages 13 to 18 · All sexes · Updated Feb 28, 2025 · NCT06851338

About Down Syndrome

About 1 in 700 babies are born with the birth defect known as Down Syndrome. Learn about the different Down Syndrome types and related health issues.

More about Down Syndrome on MedlinePlus

Down Syndrome trials in other cities

Other studies in Orange

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.