🔎 Trials Near Me

Home › Head and Neck Squamous Cell Carcinoma › Michigan › Detroit

Head and Neck Squamous Cell Carcinoma clinical trials in Detroit, MI

15 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in and around Detroit (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #65, Detroit
  • Exelixis Clinical Site #13, Detroit
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

RecruitingPhase 3
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07276399

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

RecruitingPhase 1/2
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06385080

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

RecruitingPhase 2
  • Wayne State University/Karmanos Cancer Institute, Detroit
  • Henry Ford Hospital, Detroit
  • Henry Ford Health Saint John Hospital, Detroit
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

RecruitingObservational study
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • Henry Ford Cancer Institute/Henry Ford Health System, Detroit
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06769698

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

RecruitingPhase 2/3
  • Wayne State University/Karmanos Cancer Institute, Detroit
  • Henry Ford Hospital, Detroit
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT04333537

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

RecruitingPhase 2
  • Wayne State University/Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06532279

A Study of DM005 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Henry Ford Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06515990

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

RecruitingPhase 1/2
  • Henry Ford Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

RecruitingPhase 1
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05208762

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

RecruitingPhase 1
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT07503808

A Study of DB-1310 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Henry Ford Health System, Detroit
Ages 18 and older · All sexes · Updated Apr 6, 2026 · NCT05785741

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 129, Detroit
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

A Beta-only IL-2 ImmunoTherapY Study

RecruitingPhase 1/2
  • Karmanos Cancer Institute, Detroit
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05086692

Head and Neck Squamous Cell Carcinoma trials in other cities

Other studies in Detroit

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.