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Metastatic Cancer clinical trials in Springfield, MO

6 studies for Metastatic Cancer are looking for participants at sites in and around Springfield (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • Mercy Hospital Springfield, Springfield
  • CoxHealth South Hospital, Springfield
All ages · All sexes · Updated Oct 2, 2026 · NCT05564377

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

RecruitingPhase 3
  • Oncology Hematology Associates, Springfield
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Oncology Hematology Associates, Springfield
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

RecruitingPhase 3
  • Cox Medical Center North, Springfield
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Oncology Hematology Associates, Springfield
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Collection and Storage of Tissue and Blood Samples From Patients With Cancer

RecruitingObservational study
  • Mercy Hospital Springfield, Springfield
  • CoxHealth South Hospital, Springfield
2 Months · All sexes · Updated Mar 5, 2026 · NCT02474160

Metastatic Cancer trials in other cities

Other studies in Springfield

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.