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Healthy volunteer studies in Charlotte, NC

32 studies at sites in and around Charlotte accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

RecruitingHealthy volunteers welcome
  • Novant Health Presbyterian Medical Center, Charlotte
  • Matthews Radiation Oncology Center, Matthews · 10 mi away
  • Novant Health Cancer Institute - Matthews, Matthews · 10 mi away
  • and 2 more
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07091617

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • CaroMont Regional Medical Center, Gastonia · 20 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure

RecruitingObservational studyHealthy volunteers welcome
  • Decentralized / At-Home Participation (U.S.), Charlotte
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07775495

Fertilo In Vitro Research Study and Trial

RecruitingPhase 3Healthy volunteers welcome
  • Reach Fertility, Charlotte
Ages 18 to 35 · Women · Updated Sep 29, 2026 · NCT06858111

Pancreatic Cancer Detection Consortium

RecruitingObservational studyHealthy volunteers welcome
  • Piedmont Medical Center, Rock Hill · 23 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06388967

Leveraging Chatbot to Improve PrEP in the Southern United States

RecruitingHealthy volunteers welcome
  • RAO Community Health, Charlotte
Ages 18 and older · Men · Updated Sep 23, 2026 · NCT05968755

A Study to Evaluate the Efficacy and Safety of CBL-514 Injection for Reducing Subcutaneous Fat

RecruitingPhase 3Healthy volunteers welcome
  • Investigational site 9, Charlotte
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07140939

A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, Charlotte
  • GSK Investigational Site, Denver · 23 mi away
Ages 65 and older · All sexes · Updated Sep 18, 2026 · NCT07805707

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Charlotte
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

RecruitingPhase 1/2Healthy volunteers welcome
  • Levine Cancer Insitute Carolinas Healthcare System, Charlotte
Ages 12 to 55 · All sexes · Updated Sep 9, 2026 · NCT06546670

A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.

RecruitingPhase 3Healthy volunteers welcome
  • Atrium Health Cannon Research Cente, Charlotte
  • Atrium Health - STRIVE Research clinic, Charlotte
  • Atrium Health Levine Children's Myers Park Pediatrics, Charlotte
  • and 2 more
42 Days – 211 Days · All sexes · Updated Sep 8, 2026 · NCT07629440

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Atrium Health, Charlotte
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

Reducing Risk for Infective Endocarditis

RecruitingHealthy volunteers welcome
  • Atrium Health's Carolinas Medical Center, Charlotte
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT05721781

Auditory Biofeedback Gait Training Individuals With Chronic Ankle Instability

RecruitingHealthy volunteers welcome
  • University of North Carolina at Charlotte, Charlotte
Ages 18 to 45 · All sexes · Updated Jul 21, 2026 · NCT06868316

Motiva Implants® Post-Approval Study

RecruitingHealthy volunteers welcome
  • HKB Cosmetic Surgery, Charlotte
  • Capizzi, MD Cosmetic Surgery & Med Spa, Charlotte
Ages 22 and older · Women · Updated Jul 17, 2026 · NCT06938399

Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth in/Near Infected Bone Cavities

RecruitingHealthy volunteers welcome
  • OrthoCarolina, Charlotte
Ages 22 and older · All sexes · Updated Jul 14, 2026 · NCT05361941

Evaluation of the Pathobiology of CALR-mutated MPN Cells

RecruitingObservational studyHealthy volunteers welcome
  • Atrium Health Levine Cancer, Charlotte
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT06480591

CHAAMP (CHArlotte Advocate MGUS Project) Internal Pilot Study

RecruitingObservational studyHealthy volunteers welcome
  • Atrium Health Levine Cancer, Charlotte
Ages 30 and older · All sexes · Updated Jul 13, 2026 · NCT06644625

Pre-malignant States to Hematologic Malignancies in Firefighters

RecruitingObservational studyHealthy volunteers welcome
  • Levine Cancer Institute, Charlotte
Ages 40 to 49 · All sexes · Updated Jul 13, 2026 · NCT06870760

Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54

RecruitingHealthy volunteers welcome
  • Levine Cancer Institute, Charlotte
Ages 40 to 54 · All sexes · Updated Jul 13, 2026 · NCT04577599

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients

RecruitingPhase 1Healthy volunteers welcome
  • OnSite Clinical Solutions, LLC, Charlotte
Ages 18 to 70 · All sexes · Updated Jun 15, 2026 · NCT07051629

LATe Cerclage in High-risk Pregnancies (LATCH)

RecruitingHealthy volunteers welcome
  • Atrium Health Carolinas Medical Center, Charlotte
Ages 18 to 50 · Women · Updated May 29, 2026 · NCT06036446

A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, Charlotte
12 Months – 15 Months · All sexes · Updated May 29, 2026 · NCT06740630

Study to Evaluate the REMEDY SPECTRUM GV IM Spacer Nail in the Treatment of Ankle-Related Infections

RecruitingPhase 2Healthy volunteers welcome
  • OrthoCarolina Research Institute, Charlotte
Ages 21 and older · All sexes · Updated May 19, 2026 · NCT06428448

Daoist Zhanzhuang and Human Flourishing

RecruitingHealthy volunteers welcome
  • University of North Carolina at Charlotte, Charlotte
Ages 18 to 25 · All sexes · Updated May 1, 2026 · NCT06573034

Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility

RecruitingObservational studyHealthy volunteers welcome
  • St. Jude Affiliate Clinic at Novant Health Hemby Children's Hospital, Charlotte
All ages · All sexes · Updated Apr 29, 2026 · NCT01354002

The SKyRoCKeT Study

RecruitingObservational studyHealthy volunteers welcome
  • University of North Carolina at Charlotte, Charlotte
Ages 6 to 20 · All sexes · Updated Apr 29, 2026 · NCT05770817

Safety and Effectiveness Evaluation of the High-intensity Focused Ultrasound Device for Lifting Lax Submental and Neck Tissue

RecruitingHealthy volunteers welcome
  • Dermatology, Charlotte
Ages 30 to 65 · All sexes · Updated Apr 20, 2026 · NCT07229430

A Biospecimen Collection Study of Leukapheresis-Derived Circulating Tumor Cells, Immune Cells, and Progenitor Cells.

RecruitingObservational studyHealthy volunteers welcome
  • Carolina BioOncology Institute, Huntersville · 13 mi away
Ages 5 and older · All sexes · Updated Mar 18, 2026 · NCT00571389

MiREA-AC for Reducing Problematic Alcohol and Marijuana Use in College Students

RecruitingHealthy volunteers welcome
  • University of North Carolina, Charlotte, Charlotte
Ages 18 to 26 · All sexes · Updated Jan 14, 2026 · NCT07339150

Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US

RecruitingObservational studyHealthy volunteers welcome
  • Duke University - Charlotte Study Sites, Charlotte
Ages 18 and older · All sexes · Updated Jul 24, 2025 · NCT05129345

Galactagogue Use in Lactating Women With Low Milk Supply

RecruitingHealthy volunteers welcome
  • Winthrop University, Rock Hill · 23 mi away
Ages 18 to 40 · Women · Updated Mar 28, 2025 · NCT05398367

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.